"BIRC5" Related Products

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Recombinant Human baculoviral IAP repeat-containing 5, CaM-tagged

Cat. No.: BIRC5-376H
Product Overview: Recombinant human Survivin fused to CaM-tag at N-terminus was expressed in E.coli and purified by conventional chromatography techniques, 33 kDa (294 aa).
Description: Survivin is a human gene that is part of the inhibitor of apoptosis family (IAP). The Survivin protein functions to inhibit caspase activation therefore leading to negative regulation of apoptosis or programmed cell death.
Sequences of amino acids: MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAKG SHMGAPTLPP AWQPFLKDHR ISTFKNWPFL EGCACTPERM AEAGFIHCPT ENEPDLAQCF FCFKELEGWE PDDDPIEEHK KHSSGCAFLS VKKQFEELTL GEFLKLDRER AKNKIAKETN NKKKEFEETA KKVRRAIEQL AAMD
Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 100 mM NaCl
Purity: > 90% by SDS - PAGE
Concentration: 1 mg/ml (determined by Bradford assay)
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: BIRC5 baculoviral IAP repeat-containing 5 [ Homo sapiens ]
Synonyms: BIRC5; baculoviral IAP repeat-containing 5; API4; EPR-1;apoptosis inhibitor 4; survivin variant 3 alpha; surviving; IAP4; Apoptosis inhibitor survivin; survivin variant 3 alpha
Gene ID: 332
mRNA Refseq: NM_001012270
Protein Refseq: NP_001012270
MIM: 603352
UniProt ID: O15392
Chromosome Location: 17q25
Pathway: Colorectal cancer; Cell Cycle, Mitotic
Function: Ran GTPase binding; caspase inhibitor activity; chaperone binding; cofactor binding; enzyme binding;metal ion binding; microtubule binding; peptidase inhibitor activity; protein homodimerization activity; zinc ion binding

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