"BIRC7" Related Products

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Recombinant Human Baculoviral IAP Repeat-containing 7, His-tagged

Cat. No.: BIRC7-375H
Product Overview: Recombinant human Livin fused to His-tag at N-terminus was expressed in E.coli and purified by conventional chromatography techniques, 34 kDa (318 aa).
Description: Livin is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING zinc finger (RZF) domain. Livin has direct interaction with several caspases including caspase-3, -7, and –9. This protein inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP.
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGPKDSAKCL HRGPQPSHWA AGDGPTQERC GPRSLGSPVL GLDTCRAWDH VDGQILGQLR PLTEEEEEEG AGATLSRGPA FPGMGSEELR LASFYDWPLT AEVPPELLAA AGFFHTGHQD KVRCFFCYGG LQSWKRGDDP WTEHAKWFPS CQFLLRSKGR DFVHSVQETH SQLLGSWDPW EEPEDAAPVA PSVPASGYPE LPTPRREVQS ESAQEPGGVS PAEAQRAWWV LEPPGARDVE AQLRRLQEER TCKVCLDRAV SIVFVPCGHL VCAECAPGLQ LCPICRAPVR SRVRTFLS
Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 100 mM NaCl, 2 mM EDTA, 20% glycerol
Purity: > 90% by SDS - PAGE
Concentration: 1 mg/ml (determined by Bradford assay)
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: BIRC7 baculoviral IAP repeat-containing 7 [ Homo sapiens ]
Synonyms: BIRC7; baculoviral IAP repeat-containing 7; KIAP; LIVIN; MLIAP; RNF50; ML-IAP; livin inhibitor of apoptosis; OTTHUMP00000031536; OTTHUMP00000031537; livin inhibitor-of-apoptosis; kidney inhibitor of apoptosis protein; melanoma inhibitor of apoptosis protein; baculoviral IAP repeat-containing protein 7; mliap, RNF50; livin; RING finger protein 50
Gene ID: 79444
mRNA Refseq: NM_022161
Protein Refseq: NP_071444
MIM: 605737
UniProt ID: Q96CA5
Chromosome Location: 20q13.3
Function: enzyme binding; metal ion binding; zinc ion binding

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