"CBR1" Related Products

Expand
Expand
Expand

Recombinant Human Carbonyl Reductase 1

Cat. No.: CBR1-142H
Product Overview: Recombinant human CBR1 protein was expressed in E.coli and purified by using conventional chromatography, 30 kDa (277aa).
Description: CBR1(Carbonyl reductase 1) is one of several monomericNADPH-dependentoxidoreductaseshaving wide specificity for carbonyl compounds. CBR1 is widely distributed in human tissues. CBR1 metabolizes many toxic environmentalquinonesand pharmacological relevant substrates such as the anticancerdoxorubicin. CBR1 can also convert prostaglandin E2 to prostaglandin F2-alpha.
Sequences of amino acids: MSSGIHVALV TGGNKGIGLA IVRDLCRLFS GDVVLTARDV TRGQAAVQQL QAEGLSPRFH QLDIDDLQSI RALRDFLRKE YGGLDVLVNN AGIAFKVADP TPFHIQAEVT MKTNFFGTRD VCTELLPLIK PQGRVVNVSS IMSVRALKSC SPELQQKFRS ETITEEELVG LMNKFVEDTK KGVHQKEGWP SSAYGVTKIG VTVLSRIHAR KLSEQRKGDK ILLNACCPGW VRTDMAGPKA TKSPEEGAET PVYLALLPPD AEGPHGQFVS EKRVEQW
Purity: > 95% by SDS - PAGE
Form: Liquid. In 20 mM Tris-HCl buffer (pH 8.5) containing 10% glycerol
Concentration: 1 mg/ml (determined by Bradford assay)
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: CBR1 carbonyl reductase 1 [ Homo sapiens ]
Synonyms: CBR1; CBR; hCBR1; SDR21C1; CBR1; CRN; carbonyl reductase (NADPH) 1, EC 1.1.1.184; carbonyl reductase 1; carbonyl reductase (NADPH) 1; prostaglandin 9-ketoreductase; prostaglandin-E(2) 9-reductase; short chain dehydrogenase/reductase family 21C, member 1; EC 1.1.1.184; EC 1.1.1.189; EC 1.1.1.197; NADPH-dependent carbonyl reductase 1; 15-hydroxyprostaglandin dehydrogenase [NADP+].
Gene ID: 873
mRNA Refseq: NM_001757
Protein Refseq: NP_001748
MIM: 114830
UniProt ID: P16152
Chromosome Location: 21q22.13
Pathway: Arachidonic acid metabolism
Function: 15-hydroxyprostaglandin dehydrogenase (NADP+) activity; carbonyl reductase (NADPH) activity; oxidoreductase activity; prostaglandin-E2 9-reductase activity; protein binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.