Recombinant Human MALT1, MYC/DDK-tagged

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Recombinant Human MALT1, MYC/DDK-tagged

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Cat.No. : MALT1-28H
Product Overview : Recombinant Human MALT1, transcript variant 1, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.
Description : This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Source : HEK293 cells
Species : Human
Tag : MYC/DDK
Molecular Mass : 92.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : MALT1 MALT1 paracaspase [ Homo sapiens (human) ]
Official Symbol : MALT1
Synonyms : MALT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; MLT; mucosa-associated lymphoid tissue lymphoma translocation protein 1; paracaspase; caspase-like protein; MALT associated translocation; MALT lymphoma-associated translocation; MALT-lymphoma associated translocation; MLT1; DKFZp434L132
Gene ID : 10892
mRNA Refseq : NM_006785
Protein Refseq : NP_006776
MIM : 604860
UniProt ID : Q9UDY8
Chromosome Location : 18q21
Pathway : Activation of NF-kappaB in B cells; B cell receptor signaling pathway; BCR signaling pathway
Function : cysteine-type endopeptidase activity; peptidase activity; protein binding

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