"HMOX1" Related Products

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Recombinant Human Heme Oxygenase 1, His-tagged

Cat. No. : HMOX1-137H
Product Overview : Recombinant human Heme oxygenase 1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques,31.4 kDa (274 aa).
Description : Heme oxygenase 1 belongs to the heme oxygenase family and is an essential enzyme in heme catabolism. It cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Also this protein is known to play an important role in the regulation of cardiovascular function and its adaptive response to a variety of stressors.
Sequences of amino acids : MERPQPHSMP QDLSEALKEA TKEVHTQAEN AEFMRNFQKG QVTRDGFKLV MASLYHIYVA LEEEIERNKE SPVFAPVYFP EELHRKAALE QDLAFWYGPR WQEVIPYTPA MQRYVKRLHE VGRTEPELLV AHAYTRYLGD LSGGQVLKKI AQKALDLPSS GEGLAFFTFP NIASATKFKQ LYRSRMNSLE MTPAVRQRVI EEAKTAFLLN IQLFEELQEL LTHDTKDQSP SRAPGLRQRA SNKVQDSAPV ETPRGKPPLN TRSQAPLEHH HHHH
Formulation : Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 50 mM NaCl, 0.1 mM PMSF, 10% glycerol
Purity : > 95% by SDS - PAGE
Concentration : 1 mg/ml (determined by Bradford assay)
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : HMOX1 heme oxygenase (decycling) 1 [ Homo sapiens ]
Synonyms : EC 1.14.99.3; HO; HO-1; HO1; HSP32; OTTHUMP00000028925; bK286B10; heme oxygenase (decycling) 1; heme oxygenase (decyclizing) 1;HMOX1; Heme oxygenase 1
Gene ID : 3162
mRNA Refseq : NM_002133
Protein Refseq : NP_002124
MIM : 141250
UniProt ID : P09601
Chromosome Location : 22q12; 22q13.1
Pathway : Porphyrin and chlorophyll metabolism
Function : enzyme binding; heme binding; heme oxygenase (decyclizing) activity; metal ion binding; oxidoreductase activity; phospholipase D activity; signal transducer activity

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