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Recombinant Zebrafish SF3B2

Cat.No. : SF3B2-6004Z
Product Overview : Recombinant Zebrafish SF3B2 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Zebrafish
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : sf3b2 splicing factor 3b, subunit 2 [ Danio rerio (zebrafish) ]
Official Symbol : SF3B2
Gene ID : 570994
mRNA Refseq : NM_001105277
Protein Refseq : NP_001098747
UniProt ID : A7YT51

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What are the mutation types of SF3B2? 12/17/2022

The mutation types of SF3B2 include point mutations, insertions, and deletions. Some of these mutations may cause dysfunction of the spliceosome, while others may affect its interaction with other proteins.

How to detect if there is a mutation in SF3B2? 12/12/2022

SF3B2 can be detected for mutations by gene sequencing technology. This can help doctors diagnose whether a patient has a condition related to SF3B2 and provide them with a more precise treatment plan.

How can bioinformatics methods analyze the effect of SF3B2 mutations on spliceosomes? 11/24/2022

The effect of SF3B2 mutations on spliceosomes can be analyzed by bioinformatics methods. This can predict its potential effect on the spliceosome by comparing the structure and sequence of mutant and wild-type proteins.

What are the treatment strategies for SF3B2? 04/12/2022

Therapeutic strategies for SF3B2 include inhibiting its expression, modulating its activity, or using gene therapy, among other things. For example, some studies have shown that small molecule inhibitors targeting SF3B2 can inhibit its activity and thus treat some SF3B2-related diseases. In addition, it is also possible to treat related diseases by regulating the expression level of SF3B2.

Who is at high risk of SF3B2 mutations? 10/26/2021

People with cancers such as medulloblastoma, Wilms tumor, and rhabdomyosarcoma are at high risk of SF3B2 mutations. Genetic testing of these patients can help doctors diagnose the condition more accurately and develop treatment accordingly.

What is the relationship between SF3B2 and the occurrence of the disease? 03/12/2020

Studies have shown that mutations in the SF3B2 gene are associated with the occurrence of a variety of cancers, such as medulloblastoma, Wilms tumor, rhabdomyosarcoma, etc. These mutations may cause abnormal function of the spliceosome, which in turn affects the normal growth and differentiation of cells.

Customer Reviews (3)

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Reviews
10/08/2023

    It has good crystallization properties and is suitable for analysis by X-ray crystallography.

    12/29/2021

      The SF3B2 is easy to store and has no problems with long-term storage.

      10/30/2020

        In special environments, biological activity and structural integrity can be guaranteed.

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