Recombinant Zebrafish SF3B2
Cat.No. : | SF3B2-6004Z |
Product Overview : | Recombinant Zebrafish SF3B2 full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Zebrafish |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC. |
Storage Buffer : | PBS buffer |
Gene Name : | sf3b2 splicing factor 3b, subunit 2 [ Danio rerio (zebrafish) ] |
Official Symbol : | SF3B2 |
Gene ID : | 570994 |
mRNA Refseq : | NM_001105277 |
Protein Refseq : | NP_001098747 |
UniProt ID : | A7YT51 |
Products Types
◆ Recombinant Protein | ||
Sf3b2-5810M | Recombinant Mouse Sf3b2 Protein, Myc/DDK-tagged | +Inquiry |
SF3B2-1989H | Recombinant Human SF3B2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SF3B2-1917HCL | Recombinant Human SF3B2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThe mutation types of SF3B2 include point mutations, insertions, and deletions. Some of these mutations may cause dysfunction of the spliceosome, while others may affect its interaction with other proteins.
SF3B2 can be detected for mutations by gene sequencing technology. This can help doctors diagnose whether a patient has a condition related to SF3B2 and provide them with a more precise treatment plan.
The effect of SF3B2 mutations on spliceosomes can be analyzed by bioinformatics methods. This can predict its potential effect on the spliceosome by comparing the structure and sequence of mutant and wild-type proteins.
Therapeutic strategies for SF3B2 include inhibiting its expression, modulating its activity, or using gene therapy, among other things. For example, some studies have shown that small molecule inhibitors targeting SF3B2 can inhibit its activity and thus treat some SF3B2-related diseases. In addition, it is also possible to treat related diseases by regulating the expression level of SF3B2.
People with cancers such as medulloblastoma, Wilms tumor, and rhabdomyosarcoma are at high risk of SF3B2 mutations. Genetic testing of these patients can help doctors diagnose the condition more accurately and develop treatment accordingly.
Studies have shown that mutations in the SF3B2 gene are associated with the occurrence of a variety of cancers, such as medulloblastoma, Wilms tumor, rhabdomyosarcoma, etc. These mutations may cause abnormal function of the spliceosome, which in turn affects the normal growth and differentiation of cells.
Customer Reviews (3)
Write a reviewIt has good crystallization properties and is suitable for analysis by X-ray crystallography.
The SF3B2 is easy to store and has no problems with long-term storage.
In special environments, biological activity and structural integrity can be guaranteed.
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