"LAIR1" Related Products

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Recombinant Human Leukocyte-associated Immunoglobulin-like Receptor 1, His-tagged

Cat. No.: LAIR1-348H
Product Overview: Recombinantextracellular domain of LAIR-1( 22-125aa) was overexpressed in E.coli, and purified by using conventional chromatography techniques (105 aa, 11.7 kDa).
Description: LAIR-1 is a glycoprotein(~32kDa) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells , B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region.
Source: E.coli.
Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 50 mM NaCl, 1 mM EDTA.
Molecular Weight: 11.7 kDa (105 aa).
Purity: > 95% by SDS – PAGE.
Concentration: 1 mg/ml (determined by Bradford assay).
Sequence: MQEEDLPRPS ISAEPGTVIP LGSHVTFVCR GPVGVQTFRL ERESRSTYND TEDVSQASPS ESEARFRIDS VSEGNAGPYR CIYYKPPKWS EQSDYLELLV KETSG
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: LAIR1
Synonyms: LAIR1; leukocyte-associated immunoglobulin-like receptor 1; CD305; LAIR-1; hLAIR1; CD305 antigen; leukocyte-associated Ig-like receptor 1; LAIR1 leukocyte-associated immunoglobulin-like receptor 1.
Gene ID: 3903
mRNA Refseq: NM_002287.3
Protein Refseq: NP_002278.1
MIM: 602992
UniProt ID: Q6GTX8
Chromosome Location: 19q13.4
Pathway: SNARE interactions in vesicular transport; Membrane Trafficking.
Function: protein binding; receptor activity.

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