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Recombinant Zebrafish GRK5

Cat.No. : GRK5-7708Z
Product Overview : Recombinant Zebrafish GRK5 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Zebrafish
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : grk5 G protein-coupled receptor kinase 5 [ Danio rerio (zebrafish) ]
Official Symbol : GRK5
Gene ID : 560806
mRNA Refseq : NM_001173503
Protein Refseq : NP_001166974
UniProt ID : A9JRC5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What therapeutic strategies are being explored involving GRK5 modulation? 08/21/2022

Strategies include developing GRK5 inhibitors for potential use in heart disease and Alzheimer’s.

Are there known genetic mutations in GRK5 associated with specific health conditions? 04/16/2022

Certain GRK5 polymorphisms are associated with hypertension and heart failure risk.

How is GRK5 implicated in neurodegenerative diseases? 09/06/2021

GRK5 has been linked to Alzheimer’s disease through its role in tau phosphorylation.

How does GRK5 regulate G protein-coupled receptor (GPCR) activity? 05/04/2020

It phosphorylates activated GPCRs, promoting β-arrestin binding and receptor internalization.

In which tissues or cell types is GRK5 predominantly expressed? 01/23/2020

GRK5 is widely expressed but has notable levels in the heart and brain.

What role does GRK5 play in cardiovascular function? 01/08/2020

It regulates cardiac contractility and blood pressure, influencing heart function.

What is the main function of GRK5 in cellular signaling? 04/06/2019

GRK5 phosphorylates and desensitizes GPCRs, modulating their signaling.

Customer Reviews (3)

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Reviews
09/06/2021

    Good product, fast delivery.

    05/08/2021

      Highly recommend, very satisfied.

      03/05/2021

        Worked perfectly, great quality.

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