"PPP1R1A" Related Products

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Recombinant Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1A, His-tagged

Cat. No.: PPP1R1A-341H
Product Overview: Recombinant human IPP-1, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (179 aa, 20 kDa).
Description: Protein phosphatase inhibitor-1(IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase(PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B).
Source: E.coli.
Formulation: Liquid. In 50 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 1 mM EDTA, 0.1 mM PMSF, 10% glycerol.
Molecular Weight: 20 kDa (179 aa).
Purity: > 90% by SDS – PAGE.
Concentration: 1 mg/ml (determined by Bradford assay).
Sequence: MEQDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI DEDRIPNPHL KSTLAMSPRQ RKKMTRITPT MKELQMMVEH HLGQQQQGEE PEGAAESTGT QESRPPGIPD TEVESRLGTS GTAKKTAECI PKTHERGSKE PSTKEPSTHI PPLDSKGANS VLEHHHHHH
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: PPP1R1A
Synonyms: PPP1R1A; protein phosphatase 1, regulatory (inhibitor) subunit 1A; PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A; I-1; IPP-1; IPP1; inhibitor-1; protein phosphatase inhibitor-1; Protein phosphatase inhibitor 1.
Gene ID: 5502
mRNA Refseq: NM_006741.3
Protein Refseq: NP_006732.3
UniProt ID: Q13522
Chromosome Location: 15q15.1-q15.2
Pathway: Long-term potentiation.
Function: protein binding; protein serine/threonine phosphatase inhibitor activity.

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