Recombinant Human selectin E, His-tagged
Cat.No. : | SELE-267H |
Product Overview : | Recombinant Human E-selectin comprises a 379 amino acid fragment (179-557) corresponding to the cysteine rich complement control region and is expressed in E. coli with an amino-terminal hexahistidine tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SELE-267H |
Description : | E-selectin belongs to a family of divalent cationdependent carbohydrate-binding glycoproteins or adhesion molecules. E-selectin is expressed on the surface of endothelial cells and mediates the interaction of leukocytes and platelets with endothelial cells during an inflammatory response. |
Source : | E.coli. |
Purity : | >95% by SDS-PAGE |
Form : | Liquid |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
Gene Name : | SELE selectin E [ Homo sapiens ] |
Synonyms : | SELE; CD62E; ELAM; ELAM1; ESEL; LECAM2; selectin E; OTTHUMP00000032745; endothelial adhesion molecule 1; leukocyte endothelial cell adhesion molecule 2; CD62E; ELAM-1; CD62 antigen-like family member E; CD62E antigen; Endothelial leukocyte adhesion molecule 1; Leukocyte-endothelial cell adhesion molecule 2. |
Gene ID : | 6401 |
mRNA Refseq : | NM_000450 |
Protein Refseq : | NP_000441 |
MIM : | 131210 |
UniProt ID : | P16581 |
Chromosome Location : | 1q22-q25 |
Pathway : | Cell adhesion molecules (CAMs) |
Function : | oligosaccharide binding; phospholipase binding; protein binding; sialic acid binding; sugar binding; transmembrane receptor activity |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (5)
Ask a questionSome diagnostic tests can measure SELE levels in the blood, providing insights into the inflammatory status of an individual.
Emerging research suggests a potential role of SELE in cancer metastasis, making it a target for investigation in cancer therapy.
Genetic variations can influence SELE expression, contributing to individual differences in inflammatory responses.
SELE binds to specific receptors on immune cells, facilitating their adhesion to endothelial cells and promoting their migration to inflammatory sites.
Yes, drugs designed to modulate SELE activity are being explored as potential anti-inflammatory agents.
Customer Reviews (3)
Write a reviewWith its remarkable purity and reliability, coupled with the manufacturer's excellent technical support, this protein is a crucial asset in addressing my scientific inquiries and advancing my research goals.
In addition to its outstanding quality, the SELE Protein exhibits exceptional stability during storage and usage.
Its ability to maintain structural integrity and stability ensures accurate imaging, enabling me to gain deeper insights into the three-dimensional organization and interactions of the proteins under investigation.
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