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Recombinant Human selectin E, His-tagged

Cat.No. : SELE-267H
Product Overview : Recombinant Human E-selectin comprises a 379 amino acid fragment (179-557) corresponding to the cysteine rich complement control region and is expressed in E. coli with an amino-terminal hexahistidine tag.
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  • Gene Information
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Cat. No. : SELE-267H
Description : E-selectin belongs to a family of divalent cationdependent carbohydrate-binding glycoproteins or adhesion molecules. E-selectin is expressed on the surface of endothelial cells and mediates the interaction of leukocytes and platelets with endothelial cells during an inflammatory response.
Source : E.coli.
Purity : >95% by SDS-PAGE
Form : Liquid
Storage : Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Gene Name : SELE selectin E [ Homo sapiens ]
Synonyms : SELE; CD62E; ELAM; ELAM1; ESEL; LECAM2; selectin E; OTTHUMP00000032745; endothelial adhesion molecule 1; leukocyte endothelial cell adhesion molecule 2; CD62E; ELAM-1; CD62 antigen-like family member E; CD62E antigen; Endothelial leukocyte adhesion molecule 1; Leukocyte-endothelial cell adhesion molecule 2.
Gene ID : 6401
mRNA Refseq : NM_000450
Protein Refseq : NP_000441
MIM : 131210
UniProt ID : P16581
Chromosome Location : 1q22-q25
Pathway : Cell adhesion molecules (CAMs)
Function : oligosaccharide binding; phospholipase binding; protein binding; sialic acid binding; sugar binding; transmembrane receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Is there a diagnostic test to measure SELE levels in patients? 11/30/2021

Some diagnostic tests can measure SELE levels in the blood, providing insights into the inflammatory status of an individual.

Can SELE protein be involved in cancer progression? 01/18/2020

Emerging research suggests a potential role of SELE in cancer metastasis, making it a target for investigation in cancer therapy.

Are there any genetic factors influencing SELE expression? 01/05/2018

Genetic variations can influence SELE expression, contributing to individual differences in inflammatory responses.

How does SELE protein interact with circulating immune cells? 01/09/2017

SELE binds to specific receptors on immune cells, facilitating their adhesion to endothelial cells and promoting their migration to inflammatory sites.

Can targeting SELE protein be a potential strategy for anti-inflammatory therapies? 08/05/2016

Yes, drugs designed to modulate SELE activity are being explored as potential anti-inflammatory agents.

Customer Reviews (3)

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Reviews
11/26/2020

    With its remarkable purity and reliability, coupled with the manufacturer's excellent technical support, this protein is a crucial asset in addressing my scientific inquiries and advancing my research goals.

    09/08/2019

      In addition to its outstanding quality, the SELE Protein exhibits exceptional stability during storage and usage.

      06/16/2019

        Its ability to maintain structural integrity and stability ensures accurate imaging, enabling me to gain deeper insights into the three-dimensional organization and interactions of the proteins under investigation.

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