Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Zebrafish ARF2

Cat.No. : ARF2-11548Z
Product Overview : Recombinant Zebrafish ARF2 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Zebrafish
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : arf2 ADP-ribosylation factor 2 [ Danio rerio (zebrafish) ]
Official Symbol : ARF2
Gene ID : 399477
mRNA Refseq : NM_201504
Protein Refseq : NP_958912
UniProt ID : Q7ZUA0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (30)

Ask a question
Can Arf2 interact with other members of the Arf family? 04/12/2023

Yes, Arf2 can interact with other members of the Arf family, forming heterodimers or participating in protein complexes involved in different cellular processes.

Can Arf2 regulate apoptosis? 04/11/2023

Yes, Arf2 has been shown to regulate apoptosis, or programmed cell death, by influencing the activity of pro-apoptotic and anti-apoptotic proteins.

Can Arf2 regulate cell cycle progression? 03/16/2023

Yes, Arf2 has been shown to regulate cell cycle progression by interacting with proteins involved in cell cycle control, such as cyclin-dependent kinases (Cdks) and cyclins.

Can Arf2 be involved in intercellular signaling? 02/17/2023

While Arf2 is primarily known for its intracellular functions, recent studies suggest that it may also play a role in intercellular signaling, particularly in the context of the tumor microenvironment and immune responses.

Is Arf2 essential for cell survival? 02/10/2023

Studies have shown that Arf2 is not essential for cell survival under normal conditions. However, its dysregulation can lead to disruption of cellular processes and contribute to disease progression.

How is Arf2 regulated within the cell? 09/11/2022

Arf2 activity is regulated by multiple mechanisms, including GEFs that activate it, GAPs that deactivate it, and other regulatory proteins that modulate its function and localization.

Does Arf2 play a role in cellular senescence? 08/17/2022

Yes, Arf2 is involved in cellular senescence, a state of irreversible cell cycle arrest that contributes to aging and tumor suppression. Arf2 can activate pathways leading to cellular senescence in response to various stresses.

Is Arf2 a potential therapeutic target for neurodegenerative diseases? 03/15/2022

Arf2 is being investigated as a potential therapeutic target for neurodegenerative diseases due to its involvement in pathways implicated in these diseases, such as protein aggregation and cellular stress responses.

Are there any known therapeutic strategies targeting Arf2? 01/30/2022

Therapeutic strategies targeting Arf2 include small molecule inhibitors or activators, RNA interference techniques, and gene therapies aimed at modulating its expression or activity to restore cellular equilibrium or counter disease progression.

Which proteins interact with Arf2? 01/08/2022

Arf2 interacts with various effectors and regulators to carry out its functions. Some examples include COPI and clathrin adaptor proteins, phospholipase D (PLD), and ARF-GAPs (GTPase-activating proteins).

What happens when Arf2 is mutated? 05/17/2021

Mutations in the Arf2 gene can result in functional alterations, affecting its ability to interact with other proteins or perform its normal cellular functions. These mutations can have implications for cellular processes and disease development.

Can Arf2 be targeted for drug development? 01/30/2021

Yes, Arf2 has emerged as a potential target for drug development due to its involvement in various diseases. Modulators of Arf2 activity and protein-protein interactions are being explored as potential therapeutic agents.

Is Arf2 implicated in tumor metastasis? 06/18/2020

There is limited evidence suggesting that Arf2 may play a role in tumor metastasis, although more research is needed to fully understand its involvement and mechanisms.

Is there any current research on Arf2? 02/14/2020

Yes, ongoing research focuses on uncovering the precise molecular mechanisms of Arf2-mediated cellular processes and its potential as a therapeutic target for various diseases.

Can Arf2 interact with other proteins? 12/26/2018

Yes, Arf2 can interact with various proteins, including but not limited to, p53, MDM2, E2F transcription factors, p300/CBP coactivators, p19ARF, and ribosomal proteins.

How does Arf2 contribute to cancer development? 12/10/2018

Arf2 can contribute to cancer development through various mechanisms, including its ability to inhibit cell proliferation and induce cell cycle arrest, its involvement in tumor suppressor pathways, and its interactions with oncogenic proteins.

Are there any known diseases associated with Arf2 dysregulation? 10/05/2018

Yes, dysregulation of Arf2 has been implicated in diseases such as cancer, Alzheimer's disease, Parkinson's disease, and metabolic disorders.

Can Arf2 be regulated post-translationally? 09/18/2018

Yes, Arf2 can be regulated post-translationally through modifications such as phosphorylation, acetylation, and ubiquitination, which can influence its stability, localization, and activity.

Does Arf2 have any role in DNA repair? 07/10/2017

Yes, Arf2 has been reported to participate in DNA repair processes by interacting with proteins involved in DNA damage response pathways.

Does Arf2 have any role in genomic stability? 04/30/2017

Yes, Arf2 is involved in maintaining genomic stability by regulating DNA replication, repair, and checkpoint control mechanisms.

Are there any specific Arf2 inhibitors or activators? 04/14/2017

Yes, several compounds have been developed to selectively inhibit or activate Arf2 activity. For example, brefeldin A is a well-known inhibitor, while secinH3 is an Arf-GEF-specific activator for Arf2.

Can Arf2 be involved in neuronal development and function? 12/07/2016

Yes, Arf2 has been implicated in neuronal development and function, including neurite outgrowth, synapse formation, and neurotransmitter release.

Does Arf2 play a role in embryonic development? 10/29/2016

Yes, Arf2 has been shown to be involved in embryonic development, particularly in regulating cell cycle exit and differentiation of specific cell lineages.

How is Arf2 implicated in disease? 09/11/2016

Dysregulation of Arf2 has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes, highlighting its significance in cellular homeostasis.

Can Arf2 be targeted for cancer therapy? 05/13/2016

Arf2 is being explored as a potential target for cancer therapy, as modulating its activity or expression could have therapeutic effects in certain cancer types.

Can Arf2 regulate cellular metabolism? 03/19/2016

Yes, Arf2 can regulate cellular metabolism by interacting with proteins involved in metabolic pathways, such as AMP-activated protein kinase (AMPK), and modulating energy homeostasis.

Can Arf2 be a prognostic marker for cancer? 03/15/2016

There is evidence suggesting that Arf2 expression levels can serve as a prognostic marker for certain types of cancer, including breast cancer and lung cancer.

How is Arf2 related to cellular stress responses? 03/14/2016

Arf2 is known to be involved in cellular stress responses, such as DNA damage response, oxidative stress, and endoplasmic reticulum stress, by regulating pathways that help cells cope with and survive these stresses.

Does Arf2 have any role in immune responses? 01/11/2016

Yes, Arf2 has been shown to participate in immune responses, particularly in the context of antigen presentation, T cell activation, and cytokine signaling.

Can Arf2 interact with chromatin remodeling complexes? 01/10/2016

Yes, Arf2 can interact with chromatin remodeling complexes, such as SWI/SNF and INO80, which are involved in modulating chromatin structure and gene expression.

Customer Reviews (8)

Write a review
Reviews
01/03/2023

    This flexibility allows researchers to select the most suitable form for their particular experimental setup, enhancing the efficiency and accuracy of their trials.

    08/27/2022

      The Arf2 protein exhibits remarkable performance in Western blotting (WB) experiments.

      05/13/2022

        The versatility and efficacy of Arf2 in these applications make it an invaluable tool for researchers.

        08/21/2019

          Researchers can rely on Arf2 to deliver reliable and accurate results in ELISA experiments, ensuring precise measurement and quantification of target proteins.

          04/03/2018

            researchers using the Arf2 protein can benefit from its high purity and quality, ensuring reliable results.

            12/31/2016

              With its well-characterized nature and availability in various formats, the Arf2 protein is an advantageous tool that aids researchers in achieving their scientific goals.

              11/21/2016

                the Arf2 protein is available in different formats, including recombinant and purified variants.

                02/13/2016

                  The protein's reliability and reproducibility in WB ensure accurate analysis of target proteins, while its suitability for electron microscopy structure analysis enables detailed examination of molecular structures.

                  Ask a Question for All ARF2 Products

                  Required fields are marked with *

                  My Review for All ARF2 Products

                  Required fields are marked with *

                  0

                  Inquiry Basket

                  cartIcon
                  logo

                  FOLLOW US

                  Terms and Conditions        Privacy Policy

                  Copyright © 2024 Creative BioMart. All Rights Reserved.

                  Contact Us

                  • /

                  Stay Updated on the Latest Bioscience Trends