Native Human Heparin Cofactor II

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Native Human Heparin Cofactor II

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Cat.No. : SERPIND1-12H
Product Overview : Heparin Cofactor II is a single chain glycoprotein prepared from fresh frozen human plasma.
Description : HCII is a specific inhibitor of thrombin with increased activity in the presence of heparin.
Source : Human plasma
Species : Human
Form : Frozen liquid
Molecular Mass : 65,600
Purity : >95% by SDS-PAGE analysis
Usage : For in vitro laboratory use only
Notes : Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet.
Storage : -70°C
Concentration : 5.0 mg/ml
Storage Buffer : 0.02M Tris-HCl; 0.15M NaCl; 0.02% Sodium Azide; pH 7.4
Preservative : SodiumAzide
Shipping : Dry ice
Gene Name : SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 [ Homo sapiens ]
Official Symbol : SERPIND1
Synonyms : SERPIND1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1; HCF2, serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; heparin cofactor 2; D22S673; HC II; HC2; heparin cofactor II; HLS2; serpin D1; leuserpin 2; protease inhibitor leuserpin-2; serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; LS2; HCF2; HCII; THPH10;
Gene ID : 3053
mRNA Refseq : NM_000185
Protein Refseq : NP_000176
MIM : 142360
UniProt ID : P05546
Chromosome Location : 22q11.21
Pathway : Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem;
Function : endopeptidase inhibitor activity; heparin binding; serine-type endopeptidase inhibitor activity;

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