Active Recombinant Human IGF2

• Cat.No.: IGF2-2H
• Product Overview: Human IGF-II is produced by genetically engineered yeast, and purified by sequential chromatography.

Specification

• Description: Human IGF-II is a potent mitogen for cells of mesodermal origin. It is composed of 67 amino acid residues, and is 62% homologous with human IGF-I.
• Source: yeast
• Species: Human
• Form: Lyophilized powder
• Bio-activity: The material is fully active as determined by the receptor-binding assay using a membrane preparation from placenta.
• Molecular Mass: 7.5 KDa
• Purity: Over 95% pure by N-terminal amino acid sequencing, amino acid composition, HPLC analysis, and SDS gel electrophoresis.
• Stability: Several months at +4°C.
• Storage: Store at +4°C. Reconstitution is best in water or buffer near neutral pH. After reconstitution, storage in aliquots at -80°C is recommended.

Gene Information

• Gene Name: IGF2?insulin-like growth factor 2 [?Homo sapiens?(human) ]
• Official Symbol: IGF2
• Synonyms: insulin-like growth factor 2 (somatomedin A); INSIGF; pp9974; C11orf43; FLJ22066; FLJ44734; IGF2; insulin-like growth factor 2; IGF-II; somatomedin A; somatomedin-A; insulin-like growth factor II; insulin-like growth factor type 2; putative insulin-like growth factor II associated protein; chromosome 11 open reading frame 43; OTTHUMP00000011157; OTTHUMP00000011018
• Gene ID: 3481
• mRNA Refseq: NM_000612
• Protein Refseq: NP_000603
• MIM: 147470
• UniProt ID: P01344
• Chromosome Location: 11p15.5
• Pathway: Cardiac Progenitor Differentiation; Hedgehog Signaling Pathway; IRS-related events triggered by IGF1R
• Function: growth factor activity; hormone activity; insulin receptor binding