Active Recombinant Human TNF Protein, FLAG-tagged
Cat.No. : | TNF-63H |
Product Overview : | Recombinant Human TNF-alpha with FLAG tag was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
Source : | E. coli |
Species : | Human |
Tag : | FLAG |
Form : | Lyophilized |
Bio-activity : | Induces cell death at a concentration range of 0.01-10 ng/ml (ED50= 0.05 ng/ml or 2 x 10E7 Units/mg; WEHI 164 cells). |
Molecular Mass : | ~17kDa |
Endotoxin : | <0.01 EU per 1 μg of the protein by the LAL method |
Purity : | >95% by SDS-PAGE |
Storage : | Store at -20 to -80 centigrade in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Storage Buffer : | PBS |
Reconstitution : | 10 µg size: Reconstitute with 100 µl sterile water. 50 µg size: Reconstitute with 50 µl sterile water. PBS containing at least 0.1% BSA should be used for further dilutions. |
Gene Name : | TNF tumor necrosis factor [ Homo sapiens (human) ] |
Official Symbol : | TNF |
Synonyms : | TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha; tumor necrosis factor; APC1 protein; TNF, macrophage-derived; TNF, monocyte-derived; TNF-a; cachectin; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha; tumor necrosis factor; APC1 protein; TNF, macrophage-derived; TNF, monocyte-derived; TNF-a; cachectin; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha |
Gene ID : | 7124 |
mRNA Refseq : | NM_000594 |
Protein Refseq : | NP_000585 |
MIM : | 191160 |
UniProt ID : | P01375 |
Products Types
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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