"MMP13" Related Products

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Recombinant Human MMP-13, activated

Cat.No. : MMP13-43H
Product Overview : Recombinant full-length human MMP-13 (EC 3.4.24.--) expressed in Spodoptera frugiperda (471 amino acid residues [1-mhpgvlaaf ------ rvmpansilw c-471], molecular weight 53820 Da). Swiss Prot P45452. This product is APMA activated, which had been removed after activation employing SEC and dialysis. The actMMP-13 shows predominately the app. 48-kDa form and faint the 50-kDa and app. 30-kDa form.
Source : Spodoptera frugiperda
Species : Human
Form : 50 mM Tris pH 6.5, 250 mM NaCl, 5 mM CaCl2, 1 μM ZnCl2
Bio-activity : >200 munits/mg (international unit 1 μmole/min/mg)
Purity : >95%, homogenous by SDS-PAGE
Storage : The enzyme can be kept at -80°C for many month. Repeated freezing and thawing must be avoided. Dilute and activate only the amount of enzyme you need, do not store enzyme in reaction buffer. The active 48 kDa enzyme undergoes very fast changes into a 30 kDa form which still retains enzymatic characteristics of the 48 kDa enzyme.
Gene Name : MMP13 matrix metallopeptidase 13 (collagenase 3) [ Homo sapiens ]
Official Symbol : MMP13
Synonyms : MMP13; matrix metallopeptidase 13 (collagenase 3); matrix metalloproteinase 13 (collagenase 3); collagenase 3; CLG3; MMP-13; MANDP1;
Gene ID : 4322
mRNA Refseq : NM_002427
Protein Refseq : NP_002418
MIM : 600108
UniProt ID : P45452
Chromosome Location : 11q22.3
Pathway : Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem;
Function : calcium ion binding; calcium-dependent protein binding; fibronectin binding; low-density lipoprotein particle receptor binding; metalloendopeptidase activity; peptidase activity; zinc ion binding;

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