Recombinant Mouse Pgk1, His-tagged
Cat.No. : | Pgk1-52M |
Product Overview : | Recombinant mouse Pgk1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | Pgk1 also known as Phosphoglycerate kinase 1 is an X-linked enzyme that plays a key role in the glycolytic pathway. Pgk1 acts as a polymerase alpha cofactor protein (primer recognition protein) as a glyxolytic enzyme role. This protein catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate during glycolysis, generating one molecule of ATP. |
Source : | E.coli |
Species : | Mouse |
Tag : | His |
Form : | Liquid, In Phosphate buffered saline (pH7.4) containing 10% glycerol, 1mM DTT |
Molecular Mass : | 47.1kDa (441aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSHMSLSNK LTLDKLDVKG KRVVMRVDFN VPMKNNQITN NQRIKAAVPS IKFCLDNGAK SVVLMSHLGR PDGVPMPDKY SLEPVAAELK SLLGKDVLFL KDCVGPEVEN ACANPAAGTV ILLENLRFHV EEEGKGKDAS GNKVKAEPAK IDAFRASLSK LGDVYVNDAF GTAHRAHSSM VGVNLPQKAG GFLMKKELNY FAKALESPER PFLAILGGAK VADKIQLINN MLDKVNEMII GGGMAFTFLK VLNNMEIGTS LYDEEGAKIV KDLMSKAEKN GVKITLPVDF VTADKFDENA KTGQATVASG IPAGWMGLDC GTESSKKYAE AVGRAKQIVW NGPVGVFEWE AFARGTKSLM DEVVKATSRG CITIIGGGDT ATCCAKWNTE DKVSHVSTGG GASLELLEGK VLPGVDALSN V |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by Bradford assay) |
Gene Name : | Pgk1 phosphoglycerate kinase 1 [ Mus musculus ] |
Official Symbol : | Pgk1 |
Synonyms : | PGK1; phosphoglycerate kinase 1; Pgk-1; MGC118097; |
Gene ID : | 18655 |
mRNA Refseq : | NM_008828 |
Protein Refseq : | NP_032854 |
Pathway : | Gluconeogenesis, organism-specific biosystem; Gluconeogenesis, oxaloacetate =>fructose-6P, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, conserved biosystem; Glucose metabolism, organism-specific biosystem; Glycolysis, organism-specific biosystem; |
Function : | ADP binding; ATP binding; kinase activity; nucleotide binding; phosphoglycerate kinase activity; phosphoglycerate kinase activity; transferase activity; |
Products Types
◆ Recombinant Protein | ||
PGK1-2501H | Recombinant Human PGK1 protein(21-370 aa), C-His-tagged | +Inquiry |
PGK1-3209R | Recombinant Rhesus Macaque PGK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PGK1-1310H | Recombinant Human PGK1 Protein, MYC/DDK-tagged | +Inquiry |
Pgk1-4819M | Recombinant Mouse Pgk1 Protein, Myc/DDK-tagged | +Inquiry |
PGK1-0214H | Recombinant Human PGK1 Protein (S2-I417), Tag Free | +Inquiry |
◆ Lysates | ||
PGK1-547MCL | Recombinant Mouse PGK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionPGK1 dysfunction has been associated with neurological conditions like Alzheimer's disease and Parkinson's disease due to its impact on cellular energy metabolism.
PGK1 is often upregulated in cancer cells, aiding their rapid growth and proliferation by enhancing glycolysis, known as the Warburg effect.
Research suggests that targeting PGK1 could potentially be a strategy for cancer therapy by disrupting the energy production in cancer cells.
Several compounds that modulate PGK1 activity are being studied, but none have reached widespread clinical use yet.
Yes, elevated levels of PGK1 have been identified in certain cancers, making it a potential biomarker for cancer detection and prognosis.
Customer Reviews (3)
Write a reviewmanufacturers may offer customization options, allowing researchers to tailor the PGK1 protein to their specific needs.
This may include options like different formulations, protein modifications, or tagging techniques. Customization can enhance the versatility of the protein and optimize its utility in the intended research.
They can also address any questions or concerns regarding the PGK1 protein, thereby facilitating smooth and efficient research execution.
Ask a Question for All Pgk1 Products
Required fields are marked with *
My Review for All Pgk1 Products
Required fields are marked with *
Inquiry Basket