Recombinant Human CHRNA3, His-tagged
Cat.No. : | CHRNA3-86H |
Product Overview : | Recombinant human CHRNA3 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | CHRNA3 also known as neuronal acetylcholine receptor subunit alpha-3 isoform 1 is a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. CHRNA3 is a ligand-gated ion channel that likely plays a role in neurotransmission. CHRNA3 have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer(pH8.0) containing 10% glycerol |
Molecular Mass : | 27kDa (232aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSSEAEHRL FERLFEDYNE IIRPVANVSD PVIIHFEVSM SQLVKVDEVN QIMETNLWLK QIWNDYKLKW NPSDYGGAEF MRVPAQKIWK PDIVLYNNAV GDFQVDDKTK ALLKYTGEVT WIPPAIFKSS CKIDVTYFPF DYQNCTMKFG SWSYDKAKID LVLIGSSMNL KDYWESGEWA IIKAPGYKHD IKYNCCEEIY PDITYSLYIR RL |
Purity : | >80% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by assay) |
Gene Name : | CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) [ Homo sapiens ] |
Official Symbol : | CHRNA3 |
Synonyms : | CHRNA3; cholinergic receptor, nicotinic, alpha 3 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 3; neuronal acetylcholine receptor subunit alpha-3; acetylcholine receptor; nicotinic; alpha 3 (neuronal); neuronal nicotinic acetylcholine receptor, alpha3 subunit; LNCR2; PAOD2; NACHRA3; MGC104879; |
Gene ID : | 1136 |
mRNA Refseq : | NM_000743 |
Protein Refseq : | NP_000734 |
MIM : | 118503 |
UniProt ID : | P32297 |
Chromosome Location : | 15q24 |
Pathway : | Acetylcholine Binding And Downstream Events, organism-specific biosystem; Activation of Nicotinic Acetylcholine Receptors, organism-specific biosystem; Cholinergic synapse, organism-specific biosystem; Highly calcium permeable nicotinic acetylcholine receptors, organism-specific biosystem; Highly calcium permeable postsynaptic nicotinic acetylcholine receptors, organism-specific biosystem; Highly sodium permeable acetylcholine nicotinic receptors, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; |
Function : | acetylcholine binding; acetylcholine receptor activity; acetylcholine-activated cation-selective channel activity; acetylcholine-activated cation-selective channel activity; extracellular ligand-gated ion channel activity; ligand-gated ion channel activity; receptor activity; |
Products Types
◆ Recombinant Protein | ||
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CHRNA3-2775H | Recombinant Human CHRNA3 Protein (32-240 aa), His-tagged | +Inquiry |
CHRNA3-2691H | Recombinant Human CHRNA3 Protein (32-240 aa), His-tagged | +Inquiry |
CHRNA3-5986C | Recombinant Chicken CHRNA3 | +Inquiry |
CHRNA3-1723H | Recombinant Human CHRNA3 Protein (Ser32-Leu240), N-His tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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