Recombinant Human PGM2, His-tagged

• Cat.No.: PGM2-115H
• Product Overview: Recombinant human PGM2 was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: PGM2 also known as Phosphoglucomutase-2. PGM2 is protein of the alpha-d-phosphohexomutase family and sharing about 20% identity with mammalian phosphoglucomutase 1. It acts more than 10-fold better as a phosphopentomutase than as a phosphoglucomutase.
• Source: E.coli
• Species: Human
• Tag: His
• Form: Liquid. In Phosphate buffered saline (pH7.4) containing 10% glycerol.
• Molecular Mass: 70.7kDa (635aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAAPEGS GLGEDARLDQ ETAQWLRWDK NSLTLEAVKR LIAEGNKEEL RKCFGARMEF GTAGLRAAMGPGISRMNDLT IIQTTQGFCR YLEKQFSDLK QKGIVISFDA RAHPSSGGSS RRFARLAATT FISQGIPVYL FSDITPTPFV PFTVSHLKLCAGIMITASHN PKQDNGYKVY WDNGAQIISP HDKGISQAIE ENLEPWPQAW DDSLIDSSPL LHNPSASINN DYFEDLKKYC FHRSVNRETKVKFVHTSVHG VGHSFVQSAF KAFDLVPPEA VPEQKDPDPE FPTVKYPNPE EGKGVLTLSF ALADKTKARI VLANDPDADR LAVAEKQDSGEWRVFSGNEL GALLGWWLFT SWKEKNQDRS ALKDTYMLSS TVSSKILRAI ALKEGFHFEE TLTGFKWMGN RAKQLIDQGK TVLFAFEEAIGYMCCPFVLD KDGVSAAVIS AELASFLATK NLSLSQQLKA IYVEYGYHIT KASYFICHDQ ETIKKLFENL RNYDGKNNYP KACGKFEISAIRDLTTGYDD SQPDKKAVLP TSKSSQMITF TFANGGVATM RTSGTEPKIK YYAELCAPPG NSDPEQLKKE LNELVSAIEE HFFQPQKYNLQPKAD
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: PGM2 phosphoglucomutase 2 [ Homo sapiens ]
• Official Symbol: PGM2
• Synonyms: PGM2; phosphoglucomutase 2; phosphoglucomutase-2; FLJ10983; phosphopentomutase; PGM 2; phosphodeoxyribomutase; glucose phosphomutase 2; MSTP006
• Gene ID: 55276
• mRNA Refseq: NM_018290
• Protein Refseq: NP_060760
• MIM: 172000
• UniProt ID: Q96G03
• Chromosome Location: 4p14-q12
• Pathway: Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; GDP-glucose biosynthesis, organism-specific biosystem; GDP-glucose biosynthesis, conserved biosystem; Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem; Glucose metabolism, organism-specific biosystem
• Function: isomerase activity; magnesium ion binding; phosphoglucomutase activity; phosphopentomutase activity