Recombinant Human BAG3 lysate
Cat.No. : | BAG3-56HCL |
Product Overview : | Over-expression cells lysed in RIPA buffer and lysate supplied in SDS loading buffer |
- Specification
- Gene Information
- Related Products
Source : | HEK 293 cells |
Species : | Human |
Molecular Mass : | 64090.00Da |
Recommended Usage : | WB |
Storage Instruction : | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Gene Name : | BAG3 BCL2-associated athanogene 3 [ Homo sapiens ] |
Official Symbol : | BAG3 |
Synonyms : | BAG3; BCL2-associated athanogene 3; BAG family molecular chaperone regulator 3; docking protein CAIR-1; BCL2-binding athanogene 3; bcl-2-binding protein Bis; bcl-2-associated athanogene 3; BAG-family molecular chaperone regulator-3; BIS; BAG-3; CAIR-1; MGC104307; |
Gene ID : | 9531 |
mRNA Refseq : | NM_004281 |
Protein Refseq : | NP_004272 |
MIM : | 603883 |
UniProt ID : | O95817 |
Chromosome Location : | 10q25.2-q26.2 |
Function : | chaperone binding; |
Products Types
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThe expression level of BAG3 protein can be quantitatively detected by Western blot, immunohistochemistry, real-time PCR and other technical methods.
This protein is involved in biological processes such as cardiomyocyte survival and metabolism, and plays an important role in the occurrence and progression of cardiomyopathy.
The specific regulatory mechanism of BAG3 protein can be explored to develop therapeutic strategies for its function, such as bioengineering drugs or cell gene therapy.
BAG3 protein plays an important role in regulating muscle cell life activities, metabolic processes and protein synthesis, and plays an important role in the occurrence and development of amyotrophic lateral sclerosis.
BAG3 protein plays an important role in the autophagy process, such as participating in the formation of autophagy membranes and inhibiting specific steps of autophagy pathways, affecting the occurrence and development of autophagy processes.
It is possible to develop specific targeted drugs for BAG3 protein, interfere with the binding of BAG3 protein to other apoptosis-regulatory proteins, etc., to affect the growth and metastasis of tumor cells.
Customer Reviews (3)
Write a reviewWith its wide applicability, it can play a key role in many fields of research and promote the progress of science.
The short half-life and high clearance properties of this recombinant protein make it a higher potential in drug research and development, which is expected to become a new generation of therapeutic drugs.
It's the most biologically active protein I've ever seen, and the purity of its production is impressive.
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