Recombinant Human MYH9, GST-tagged MYH9-31H

Recombinant Human MYH9, GST-tagged

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Recombinant Human MYH9, GST-tagged

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Cat.No. : MYH9-31H
Product Overview : Recombinant Human MYH9(1747 a.a. - 1852 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ.
Description : This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
Source : Wheat germ
Species : Human
Tag : GST
Molecular Mass : 37.4 kDa
AA Sequence : LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE QLDNETKERQAACKQVRRTEKKLKDVLLQVD
Applications : ELISA; WB-Re; AP; Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : MYH9 myosin, heavy chain 9, non-muscle [ Homo sapiens (human) ]
Official Symbol : MYH9
Synonyms : MYH9; myosin, heavy chain 9, non-muscle; DFNA17, myosin, heavy polypeptide 9, non muscle; myosin-9; EPSTS; FTNS; MHA; NMHC II A; NMMHCA; nonmuscle myosin heavy chain II A
Gene ID : 4627
mRNA Refseq : NM_002473
Protein Refseq : NP_002464
MIM : 160775
UniProt ID : P35579
Chromosome Location : 22q13.1
Pathway : Axon guidance; Developmental Biology; EPHA-mediated growth cone collapse; Regulation of actin cytoskeleton
Function : ADP binding; contributes_to actin filament binding; contributes_to actin-dependent ATPase activity

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