Recombinant Human MYH9, His-tagged
Cat.No. : | MYH9-29659TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 1130-1960 of Human non-muscle Myosin IIA with N terminal His tag; 831 amino acids, 110kDa. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 1130-1960 a.a. |
Description : | This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. |
Conjugation : | HIS |
Tissue specificity : | In the kidney, expressed in the glomeruli. Also expressed in leukocytes. |
Form : | Lyophilised:Reconstitute with 51 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | AEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEV NILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQ TKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKR KKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNV TGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ KLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLH AQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRH EEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL EKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVG KSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME AELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEK KLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA NSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIN DRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKE LKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNET KERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQA DKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATE TADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGS DEEVDGKADGAEAKPAE |
Sequence Similarities : | Contains 1 IQ domain.Contains 1 myosin head-like domain. |
Gene Name | MYH9 myosin, heavy chain 9, non-muscle [ Homo sapiens ] |
Official Symbol | MYH9 |
Synonyms | MYH9; myosin, heavy chain 9, non-muscle; DFNA17, myosin, heavy polypeptide 9, non muscle; myosin-9; EPSTS; FTNS; MHA; NMHC II A; NMMHCA; nonmuscle myosin heavy chain II A; |
Gene ID | 4627 |
mRNA Refseq | NM_002473 |
Protein Refseq | NP_002464 |
MIM | 160775 |
Uniprot ID | P35579 |
Chromosome Location | 22q13.1 |
Pathway | Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Regulation of actin cytoskeleton, organism-specific biosystem; Regulation of actin cytoskeleton, conserved biosystem; Salmonella infection, organism-specific biosystem; |
Function | ADP binding; ATP binding; ATP binding; ATPase activity; actin binding; |
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Not For Human Consumption!
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