| Species : |
Human |
| Source : |
E.coli |
| Tag : |
His |
| Protein Length : |
1130-1960 a.a. |
| Description : |
This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. |
| Conjugation : |
HIS |
| Tissue specificity : |
In the kidney, expressed in the glomeruli. Also expressed in leukocytes. |
| Form : |
Lyophilised:Reconstitute with 51 μl aqua dest. |
| Storage buffer : |
Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
| Storage : |
Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : |
AEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEV NILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQ TKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKR KKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNV TGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ KLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLH AQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRH EEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL EKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVG KSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME AELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEK KLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA NSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIN DRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKE LKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNET KERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQA DKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATE TADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGS DEEVDGKADGAEAKPAE |
| Sequence Similarities : |
Contains 1 IQ domain.Contains 1 myosin head-like domain. |
