Recombinant Human GDF3

• Cat.No.: GDF3-246H
• Product Overview: Recombinant Human GDF3 was expressed in CHO cell.

Specification

• Description: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.
• Source: CHO
• Species: Human
• Form: Lyophilized. This recombinant protein was lyophilized from a 0.2 μm filtered solution in hydrogen chloride (HCl).
• Molecular Mass: The predicted molecular weight of Recombinant Human GDF-3 is Mr 12.9 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 18 kDa, reducing conditions kDa.
• AA Sequence: aaipvpklsc knlchrhqlf infrdlgwhk wiiapkgfma nychgecpfs ltislnssny afmqalmhav dpeipqavci ptklspisml yqdnndnvil rhyedmvvde cgcg
• Endotoxin: <1.0 EU/µg as determined by the LAL method
• Purity: >90% by SDS-PAGE and analyzed by silver stain.
• Storage: This lyophilized protein is stable for six to twelve months when stored desiccated at -20ºC to -70ºC. After aseptic reconstitution, this protein may be stored at 2ºC to 8ºC for one month or at -20ºC to -70ºC in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: GDF3 growth differentiation factor 3 [ Homo sapiens (human) ]
• Official Symbol: GDF3
• Synonyms: GDF3; growth differentiation factor 3; KFS3; MCOP7; MCOPCB6; growth/differentiation factor 3; GDF-3
• Gene ID: 9573
• mRNA Refseq: NM_020634
• Protein Refseq: NP_065685
• MIM: 606522
• UniProt ID: Q9NR23
• Chromosome Location: 12p13.1
• Function: cytokine activity; growth factor activity; protein kinase binding; transforming growth factor beta receptor binding