"LGALS3BP" Related Products

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Recombinant Human LGALS3BP, His-tagged

Cat.No.: LGALS3BP-156H
Product Overview: Recombinant Human LGALS3BP(Val19-Asp585 & Tyr455-Asp585), fused with C-terminal 10-His tag, was expressed in Mouse NSO Cells.
Description: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
Source: Mouse NSO Cells
Species: Human
Tag: His
Predicted N Terminal: Val19 & Tyr455
Form: Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human (rh) Galectin3BP/MAC2BP at 0.1 µg/mL can bind rhGalectin-3 with an apparent KD <20 nM.
Molecular Mass: Predicted Molecular Mass:64.6 kDa, 48.7 kDa & 16 kDaSDS-PAGE:90-95 kDa, 63-66 kDa and 26-27 kDa, reducing conditions
Endotoxin: < 1.0 EU per 1 μg of the protein by the LAL method.
Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 ºC as supplied.1 month, 2 to 8 ºC under sterile conditions after reconstitution.3 months, -20 to -70 ºC under sterile conditions after reconstitution.
Reconstitution: Reconstitute at 100 µg/mL in sterile PBS.
Gene Name: LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein [ Homo sapiens (human) ]
Official Symbol: LGALS3BP
Synonyms: LGALS3BP; lectin, galactoside-binding, soluble, 3 binding protein; 90K; BTBD17B; MAC-2-BP; L3 antigen; galectin 3 binding protein; serum protein 90K; Mac-2-binding protein
Gene ID: 3959
mRNA Refseq: NM_005567
Protein Refseq: NP_005558
MIM: 600626
UniProt ID: Q08380
Chromosome Location: 17q25
Function: scavenger receptor activity

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