Recombinant Human DDX58, MYC/DDK-tagged


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Recombinant Human DDX58, MYC/DDK-tagged

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Cat.No. : DDX58-11H
Product Overview : Recombinant Human DDX58, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.
Description : DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.
Source : HEK293 cells
Species : Human
Molecular Mass : 106.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 [ Homo sapiens (human) ]
Official Symbol : DDX58
Synonyms : DDX58; RIGI; RIG-I; RLR-1; RIG-1; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; probable ATP-dependent RNA helicase DDX58; RNA helicase RIG-I; DEAD box protein 58; RIG-I-like receptor 1; retinoic acid inducible gene I; retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; EC; DKFZp434J1111; FLJ13599
Gene ID : 23586
mRNA Refseq : NM_014314
Protein Refseq : NP_055129
MIM : 609631
UniProt ID : O95786
Chromosome Location : 9p12
Pathway : Antiviral mechanism by IFN-stimulated genes; Cytokine Signaling in Immune system; Cytosolic DNA-sensing pathway; Epstein-Barr virus infection; Herpes simplex infection
Function : ATP binding; ATP-dependent helicase activity; double-stranded DNA binding; double-stranded RNA binding; identical protein binding; protein binding; single-stranded RNA binding; zinc ion binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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