Recombinant Human DDX58, MYC/DDK-tagged DDX58-11H

Recombinant Human DDX58, MYC/DDK-tagged

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Recombinant Human DDX58, MYC/DDK-tagged

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Cat.No. : DDX58-11H
Product Overview : Recombinant Human DDX58, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.
Description : DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.
Source : HEK293 cells
Species : Human
Tag : MYC/DDK
Molecular Mass : 106.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 [ Homo sapiens (human) ]
Official Symbol : DDX58
Synonyms : DDX58; RIGI; RIG-I; RLR-1; RIG-1; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; probable ATP-dependent RNA helicase DDX58; RNA helicase RIG-I; DEAD box protein 58; RIG-I-like receptor 1; retinoic acid inducible gene I; retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; EC 3.6.4.13; DKFZp434J1111; FLJ13599
Gene ID : 23586
mRNA Refseq : NM_014314
Protein Refseq : NP_055129
MIM : 609631
UniProt ID : O95786
Chromosome Location : 9p12
Pathway : Antiviral mechanism by IFN-stimulated genes; Cytokine Signaling in Immune system; Cytosolic DNA-sensing pathway; Epstein-Barr virus infection; Herpes simplex infection
Function : ATP binding; ATP-dependent helicase activity; double-stranded DNA binding; double-stranded RNA binding; identical protein binding; protein binding; single-stranded RNA binding; zinc ion binding

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