Recombinant Human CHKA, MYC/DDK-tagged

• Cat.No.: CHKA-65H
• Product Overview: Recombinant Human CHKA, transcript variant 2, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Description: The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293 cells
• Species: Human
• Tag: MYC/DDK
• Molecular Mass: 50 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: CHKA choline kinase alpha [ Homo sapiens (human) ]
• Official Symbol: CHKA
• Synonyms: CHKA; choline kinase alpha; CK; EK; CHK; CKI; choline kinase; CHETK-alpha; ethanolamine kinase; NP_001268.2; EC 2.7.1.32; NP_997634.1
• Gene ID: 1119
• mRNA Refseq: NM_212469
• Protein Refseq: NP_997634
• MIM: 118491
• UniProt ID: P35790
• Chromosome Location: 11q13.2
• Pathway: Acetylcholine Synthesis; Choline metabolism in cancer; Glycerophospholipid biosynthesis; Metabolic pathways
• Function: ATP binding; choline binding; choline kinase activity