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Recombinant Human RAD52

Cat.No. : RAD52-135H
Product Overview : The product was highly purified from E. coli over-expressing human Rad52 protein as a recombinant protein.
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  • Gene Information
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Description : Human Rad52 protein plays a major role in genetic recombination and recombination repair by mediating strand-annealing reaction between complementary DNA strands. Rad52 functionally and physically interacts with Rad51, Dmc1, and RPA in recombination processes. In radiation damaged cells, Rad52 is phosphorylated at Tyr104 by c-Abl tyrosine kinase and forms nuclear foci.
Source : E. coli
Species : Human
Form : 20 mM potassium phosphate pH 7.5, 200 mM KCl, 2 mM 2ME, 0.5 mM EDTA, 20% glycerol
Purity : >90% as judged from SDS-PAGE analysis
Applications : 1) Studies on homologous recombination in mammals including human 2) Studies on the interaction of Rad52 protein with various proteins 3) To be used as a standard for Western blotting
Storage : Store at -70℃.
Gene Name : RAD52 RAD52 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : RAD52
Synonyms : RAD52; RAD52 homolog (S. cerevisiae); RAD52 (S. cerevisiae) homolog; DNA repair protein RAD52 homolog; recombination protein RAD52; rhabdomyosarcoma antigen MU-RMS-40.23;
Gene ID : 5893
mRNA Refseq : NM_134424
Protein Refseq : NP_602296
MIM : 600392
UniProt ID : P43351
Chromosome Location : 12p13-p12.2
Pathway : Assembly of the RAD51-ssDNA nucleoprotein complex, organism-specific biosystem; DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Homologous DNA pairing and strand exchange, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem; Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem;
Function : DNA binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does RAD52 relate to the 53BP1 protein? 11/09/2022

RAD5 inhibits the expression of 53BP1 protein.

Where is the RAD52 primarily located? 01/14/2022

RAD52 is mainly localized in the nucleus.

What are the effects of RAD52 deficiency? 01/02/2022

RAD52 deletion shortens cell survival by increasing damage-induced chromosomal abnormalities and decreasing HRR repair efficiency period.

What diseases is RAD52 closely related to the study of? 11/23/2020

RAD52 is associated with the study of lung, stomach, and nasopharyngeal cancers.

What biological processes is RAD52 involved in? 09/22/2020

RAD52 is involved in cell biological processes such as meiosis, mitotic recombination and maintenance of genome stability.

Customer Reviews (3)

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Reviews
11/10/2022

    Fast and timely shipment helped me to get satisfactory experimental results in short time.

    03/12/2022

      The RAD52 proteins purchased from your company is suitable for ELISA.

      11/21/2020

        The staff was very nice, communicated with me positively and solved a lot of technical problems.

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