Recombinant Human RAD52 RAD52-135H

Recombinant Human RAD52

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Recombinant Human RAD52

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Cat.No. : RAD52-135H
Product Overview : The product was highly purified from E. coli over-expressing human Rad52 protein as a recombinant protein.
Description : Human Rad52 protein plays a major role in genetic recombination and recombination repair by mediating strand-annealing reaction between complementary DNA strands. Rad52 functionally and physically interacts with Rad51, Dmc1, and RPA in recombination processes. In radiation damaged cells, Rad52 is phosphorylated at Tyr104 by c-Abl tyrosine kinase and forms nuclear foci.
Source : E. coli
Species : Human
Form : 20 mM potassium phosphate pH 7.5, 200 mM KCl, 2 mM 2ME, 0.5 mM EDTA, 20% glycerol
Purity : >90% as judged from SDS-PAGE analysis
Applications : 1) Studies on homologous recombination in mammals including human 2) Studies on the interaction of Rad52 protein with various proteins 3) To be used as a standard for Western blotting
Storage : Store at -70℃.
Gene Name : RAD52 RAD52 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : RAD52
Synonyms : RAD52; RAD52 homolog (S. cerevisiae); RAD52 (S. cerevisiae) homolog; DNA repair protein RAD52 homolog; recombination protein RAD52; rhabdomyosarcoma antigen MU-RMS-40.23;
Gene ID : 5893
mRNA Refseq : NM_134424
Protein Refseq : NP_602296
MIM : 600392
UniProt ID : P43351
Chromosome Location : 12p13-p12.2
Pathway : Assembly of the RAD51-ssDNA nucleoprotein complex, organism-specific biosystem; DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Homologous DNA pairing and strand exchange, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem; Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem;
Function : DNA binding; protein binding;

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