||The product was highly purified from E. coli over-expressing human Rad52 protein as a recombinant protein.
||Human Rad52 protein plays a major role in genetic recombination and recombination repair by mediating strand-annealing reaction between complementary DNA strands. Rad52 functionally and physically interacts with Rad51, Dmc1, and RPA in recombination processes. In radiation damaged cells, Rad52 is phosphorylated at Tyr104 by c-Abl tyrosine kinase and forms nuclear foci.
||20 mM potassium phosphate pH 7.5, 200 mM KCl, 2 mM 2ME, 0.5 mM EDTA, 20% glycerol
||>90% as judged from SDS-PAGE analysis
||1) Studies on homologous recombination in mammals including human 2) Studies on the interaction of Rad52 protein with various proteins 3) To be used as a standard for Western blotting
||Store at -70℃.