Recombinant Human RETNLB

• Cat.No.: RETNLB-50H
• Product Overview: Recombinant Human RELMβ is a 19.0 kDa protein, consisting of two identical 89 amino acid polypeptide chains linked by a single disulfide bond.

Specification

• Description: RELMβ (Resistin-like molecule β/FIZZ2) is a disulfide-linked, homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELMβ, and its molecular targets, are not fully known, but it has been suggested that it plays a regulatory role during inflammation, and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly, the molecular structure of RELMβ is highly homologous to that of the adipose-derived cytokines, resistin and RELMα. These proteins share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C.
• Source: E.coli
• Species: Human
• AA Sequence: MQCSLDSVMD KKIKDVLNSL EYSPSPISKK LSCASVKSQG RPSSCPAGMA VTGCACGYGC GSWDVQLETT CHCQCSVVDW TTARCCHLT
• Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

Gene Information

• Gene Name: RETNLB resistin like beta [ Homo sapiens (human) ]
• Official Symbol: RETNLB
• Synonyms: RETNLB; resistin like beta; XCP2; FIZZ1; FIZZ2; HXCP2; RELMb; RELMbeta; RELM-beta; found in inflammatory zone 1; cysteine-rich secreted A12-alpha-like protein 1; colon and small intestine-specific cysteine-rich protein; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 2; CCRG; RETNL2
• Gene ID: 84666
• mRNA Refseq: NM_032579
• Protein Refseq: NP_115968
• MIM: 605645
• UniProt ID: Q9BQ08
• Chromosome Location: 3q13.1
• Pathway: IL4-mediated signaling events
• Function: hormone activity; molecular_function