"RAB7A" Related Products

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Recombinant Human RAB7A, His-tagged

Cat.No.: RAB7A-194H
Product Overview: Recombinant human RAB7A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Source: E.Coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 100mM NaCl
Molecular Mass: 25.6 kDa (227aa), confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSHQSLGVAFYRG ADCCVLVFDV TAPNTFKTLD SWRDEFLIQA SPRDPENFPF VVLGNKIDLE NRQVATKRAQ AWCYSKNNIP YFETSAKEAINVEQAFQTIA RNALKQETEV ELYNEFPEPI KLDKNDRAKA SAESCSC MTSRKKVLLK VIILGDSGVG KTSLMNQYVN KKFSNQYKAT IGADFLTKEV MVDDRLVTMQ IWDTAGQERF
Purity: > 90% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)
Gene Name: RAB7A RAB7A, member RAS oncogene family [ Homo sapiens (human) ]
Official Symbol: RAB7A
Synonyms: RAB7A; RAB7A, member RAS oncogene family; RAB7; PRO2706; ras-related protein Rab-7a; RAB7, member RAS oncogene family; Ras-associated protein RAB7
Gene ID: 7879
mRNA Refseq: NM_004637
Protein Refseq: NP_004628
MIM: 602298
UniProt ID: P51149
Chromosome Location: 3q21.3
Pathway: Adaptive Immune System; Immune System; Salmonella infection
Function: GDP binding; GTP binding; GTPase activity; Rac GTPase binding

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