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Recombinant Human VWF protein, Met/His-tagged

Cat.No.: VWF-2712H
Product Overview: Recombinant Human VWF(Asp1498-Val1665) fused with Met/His tag at N-terminal was expressed in E. coli.
Source: E. coli
Species: Human
Tag: Met/His
Predicted N Terminal: Met
Form: Supplied as a 0.2 μm filtered solution in Tris, NaCl and Glycerol.
Bio-activity: Measured by its ability to be used as a protein substrate for ADAMTS13. >50% of rhvWF-A2 is cleaved as measured under the described conditions.
Molecular Mass: Predicted Molecular Mass: 20 kDa;SDS-PAGE: 18 kDa, reducing conditions.
Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Storage: Avoid repeated freeze-thaw cycles.6 months from date of receipt, -20 to -70 centigrade as supplied.3 months, -20 to -70 centigrade under sterile conditions after opening.
Gene Name: VWF von Willebrand factor [ Homo sapiens ]
Official Symbol: VWF
Synonyms: VWF; von Willebrand factor; F8VWF; coagulation factor VIII VWF; VWD;
Gene ID: 7450
mRNA Refseq: NM_000552
Protein Refseq: NP_000543
MIM: 613160
UniProt ID: P04275
Chromosome Location: 12p13.3
Pathway: Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem;
Function: chaperone binding; collagen binding; glycoprotein binding; immunoglobulin binding; integrin binding; protease binding; protease binding; protein N-terminus binding; protein binding; protein homodimerization activity;

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