| Cat.No.: | UL146-201C |
| Product Overview: | Recombinant CMV UL146 (Accession # AAA85885) Thr23-Gly117 was produced in E. coli-derived. |
| Source: | E. coli |
| Species: | CMV |
| Predicted N Terminal: | Thr23 |
| Form: | Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein. |
| Bio-activity: | Measured by its ability to induce myeloperoxidase release from cytochalasin B-treated human neutrophils. Schröder, J.M. et al. (1987) J. Immunol. 139:3474.The ED50 for this effect is typically 0.3 - 0.6 µg/mL.Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2.The ED50 for this effect is typically 0.03 - 0.18 µg/mL. |
| Molecular Mass: | Recombinant CMV UL146 has a calculated MW of 11.1 kDa. |
| Purity: | >97%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
| Storage: | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
| Reconstitution: | Reconstitute at 25 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
| Gene Name: | UL146 contains signal peptide; putative secreted glycoprotein; involved in immune regulation [ Human herpesvirus 5 (Human cytomegalovirus) ] |
| Official Symbol: | UL146 |
| Synonyms: | UL146; contains signal peptide; putative secreted glycoprotein; involved in immune regulation; chemokine vCXCL1; YP_081571.1; CXCL family |
| Gene ID: | 3077566 |
| mRNA Refseq: | |
| Protein Refseq: | YP_081571 |
| MIM: | |
| UniProt ID: | Q6SW20 |
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