Active Recombinant CMV UL146

• Cat.No.: UL146-201C
• Product Overview: Recombinant CMV UL146 (Accession # AAA85885) Thr23-Gly117 was produced in E. coli-derived.

Specification

• Source: E. coli
• Species: CMV
• Predicted N Terminal: Thr23
• Form: Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
• Bio-activity: Measured by its ability to induce myeloperoxidase release from cytochalasin B-treated human neutrophils. Schröder, J.M. et al. (1987) J. Immunol. 139:3474.The ED50 for this effect is typically 0.3 - 0.6 µg/mL.Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2.The ED50 for this effect is typically 0.03 - 0.18 µg/mL.
• Molecular Mass: Recombinant CMV UL146 has a calculated MW of 11.1 kDa.
• Purity: >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 25 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: UL146 contains signal peptide; putative secreted glycoprotein; involved in immune regulation [ Human herpesvirus 5 (Human cytomegalovirus) ]
• Official Symbol: UL146
• Synonyms: UL146; contains signal peptide; putative secreted glycoprotein; involved in immune regulation; chemokine vCXCL1; YP_081571.1; CXCL family
• Gene ID: 3077566
• Protein Refseq: YP_081571
• UniProt ID: Q6SW20