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Active Recombinant Mouse Sfrp2, His-tagged

Cat.No. : Sfrp2-223M
Product Overview : Recombinant Mouse Sfrp2 (Accession # AAB70795) Leu25-Cys295, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived.
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  • Gene Information
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Source : Mammalian cells
Species : Mouse
Tag : His
Predicted N Terminal : Leu25
Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Measured by its ability to compete with Frizzled-1 for binding to biotinylated Wnt-3a.The IC50 value is 0.7-3.5 nM, under conditions in which Recombinant Mouse (rm) Frizzled-1 Fc Chimera is present at 2.1 nM, and biotinylated rmWnt-3a concentration is 2.7 nM.
Molecular Mass : Recombinant Mouse Sfrp2, His-tagged has a calculated MW of 31.6 kDa. In SDS-PAGE migrates as 35-40 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : Sfrp2 secreted frizzled-related protein 2 [ Mus musculus ]
Official Symbol : Sfrp2
Synonyms : SFRP2; secreted frizzled-related protein 2; SARP-1; sFRP-2; stromal cell derived factor 5; secreted apoptosis-related protein 1; secreted frizzled-related sequence protein 2; secreted frizzled-related sequence protein 5; Sdf5; AI851596;
Gene ID : 20319
mRNA Refseq : NM_009144
Protein Refseq : NP_033170
MIM :

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does SFRP2 expression influence stem cell differentiation and regeneration in various tissues? 01/11/2022

SFRP2 expression plays a significant role in stem cell differentiation, contributing to tissue regeneration and repair processes.

What role does SFRP2 play in the development and progression of cardiovascular diseases, especially atherosclerosis? 08/22/2021

In cardiovascular diseases, SFRP2 plays a role in processes like atherosclerosis, impacting vascular health and disease progression.

What is the impact of SFRP2 on angiogenesis in the context of tumor growth and metastasis? 02/20/2021

SFRP2 influences angiogenesis in tumors, affecting tumor growth and the potential for metastasis.

How does SFRP2 interact with Wnt signaling pathways in cancer development, particularly in colorectal and breast cancers? 11/06/2020

SFRP2 modulates Wnt signaling in cancers, with specific roles in colorectal and breast cancer development, impacting cell proliferation and migration.

How does SFRP2 modulate bone formation and resorption in osteoporosis and other bone diseases? 05/24/2020

SFRP2 is involved in bone metabolism, affecting bone formation and resorption in diseases like osteoporosis.

What are the mechanisms by which SFRP2 contributes to fibrosis in organ systems like the heart and liver? 03/02/2020

SFRP2 contributes to fibrosis in organs like the heart and liver, influencing tissue remodeling and function.

How does the alteration of SFRP2 expression affect adipogenesis and metabolic processes in obesity and diabetes? 11/17/2018

Alterations in SFRP2 expression affect adipogenesis and metabolic functions, linking it to obesity and diabetes pathologies.

Customer Reviews (3)

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Reviews
11/13/2021

    Fast and affordable protein sequencing; great for identifying unknown proteins.

    04/28/2019

      Robust protein-protein interaction assays; pivotal for our experiments.

      02/20/2018

        High-quality protein crystallization; crucial for structural biology studies.

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