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Recombinant Human FLT1, Fc Chimera

Cat.No.: FLT1-241H
Product Overview: Recombinant Human FLT1 (Accession # AAC50060) was produced in Spodoptera frugiperda, Sf 21 (baculovirus)-derived.
Source: Baculovirus Sf 21 Insect cells
Species: Human
Tag: Fc Chimera
Predicted N Terminal: Ser27
Form: Lyophilized from a 0.2 µm filtered solution in MOPS, NaCl and CHAPS with BSA as a carrier protein.
Bio-activity: Measured by its ability to inhibit the VEGF-dependent proliferation of HUVEC human umbilical vein endothelial cells. Conn, G. et al. (1990) Proc. Natl. Acad. Sci. USA 87:1323.The ED50 for this effect is typically 5-30 ng/mL.
Molecular Mass: Recombinant Human FLT1, Fc Chimera has a calculated MW of 100 kDa (monomer). In SDS-PAGE migrates as 123 kDa, reducing conditions.
Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution: Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name: FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) [ Homo sapiens ]
Official Symbol: FLT1
Synonyms: FLT1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FLT; vascular endothelial growth factor receptor 1; VEGFR1; FLT-1; VEGFR-1; fms-like tyrosine kinase 1; tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; vascular permeability factor receptor;
Gene ID: 2321
mRNA Refseq: NM_001159920
Protein Refseq: NP_001153392
MIM: 165070
UniProt ID: P17948
Chromosome Location: 13q12

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