Active Recombinant Human XIAP

• Cat.No.: XIAP-243H
• Product Overview: Recombinant Human XIAP (Accession # AAC50373) was produced in E. coli-derived.

Specification

• Source: E. coli
• Species: Human
• Predicted N Terminal: Ala
• Form: Supplied as a 0.2 µm filtered solution in HEPES, NaCl, DTT and Glycerol.
• Bio-activity: Measured by its ability to inhibit DEVD-AFC cleavage activity by Recombinant Human Caspase-7 .The IC50 for inhibition of rhCaspase-7 activity is <50 nM, as measured under the described conditions.
• Molecular Mass: Recombinant Human XIAP has a calculated MW of 58 kDa. In SDS-PAGE migrates as 54-56 kDa, reducing conditions.
• Purity: >85%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: XIAP X-linked inhibitor of apoptosis [ Homo sapiens ]
• Official Symbol: XIAP
• Synonyms: XIAP; X-linked inhibitor of apoptosis; API3, baculoviral IAP repeat containing 4 , BIRC4; baculoviral IAP repeat-containing protein 4; hILP; X-linked IAP; IAP-like protein; E3 ubiquitin-protein ligase XIAP; inhibitor of apoptosis protein 3; baculoviral IAP repeat-containing 4; X-linked inhibitor of apoptosis protein; API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3; FLJ26913
• Gene ID: 331
• mRNA Refseq: NM_001167
• Protein Refseq: NP_001158
• MIM: 300079
• UniProt ID: P98170
• Chromosome Location: Xq25