Recombinant Human TNFRSF10A, Fc Chimera TNFRSF10A-249H

Recombinant Human TNFRSF10A, Fc Chimera

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Recombinant Human TNFRSF10A, Fc Chimera

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Cat.No. : TNFRSF10A-249H
Product Overview : Recombinant Human TNFRSF10A (Accession # AAC51226) was produced in Chinese Hamster Ovary cell line, CHO-derived.
Source : CHO cells
Species : Human
Tag : Fc Chimera
Predicted N Terminal : Ala109
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL.The ED50 for this effect is typically 0.25 - 1.25 ng/mL in the presence of 6 ng/mL of Recombinant Human TRAIL/TNFSF10.
Molecular Mass : Recombinant Human TNFRSF10A, Fc Chimera has a calculated MW of 40.9 kDa (monomer). In SDS-PAGE migrates as 50-55 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : TNFRSF10A tumor necrosis factor receptor superfamily, member 10a [ Homo sapiens ]
Official Symbol : TNFRSF10A
Synonyms : TNFRSF10A; tumor necrosis factor receptor superfamily, member 10a; tumor necrosis factor receptor superfamily member 10A; Apo2; CD261; DR4; TRAILR 1; TRAIL-R1; TRAIL receptor 1; death receptor 4; cytotoxic TRAIL receptor; TNF-related apoptosis-inducing ligand receptor 1; tumor necrosis factor receptor superfamily member 10a variant 2; APO2; TRAILR1; TRAILR-1; MGC9365;
Gene ID : 8797
mRNA Refseq : NM_003844
Protein Refseq : NP_003835
MIM : 603611
UniProt ID : O00220
Chromosome Location : 8p21

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