Active Recombinant Mouse Fcgrt, His-tagged

• Cat.No.: Fcgrt-291M
• Product Overview: Recombinant Mouse Fcgrt (Accession # AAH03786) Ser22-Val301, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Mouse
• Tag: His
• Predicted N Terminal: Ser22
• Form: Lyophilized from a 0.2 µm filtered solution in PBS, NaCl and Triton
• Bio-activity: Measured by its binding ability in a functional ELISA.When Recombinant Mouse FCRN is immobilized at 0.5 µg/mL (100 µL/well), the concentration of human IgG that produces 50% of the optimal binding response is found to be approximately 2 - 10 µg/mL.
• Molecular Mass: Recombinant Mouse Fcgrt, His-tagged has a calculated MW of 32.3 kDa. In SDS-PAGE migrates as 45-47 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Fcgrt Fc receptor, IgG, alpha chain transporter [ Mus musculus ]
• Official Symbol: Fcgrt
• Synonyms: FCGRT; Fc receptor, IgG, alpha chain transporter; IgG receptor FcRn large subunit p51; neonatal Fc receptor; igG Fc fragment receptor transporter alpha chain; FcRn
• Gene ID: 14132
• mRNA Refseq: NM_010189
• Protein Refseq: NP_034319