Active Recombinant Mouse Ifnlr1, Fc Chimera

• Cat.No.: Ifnlr1-341M
• Product Overview: Recombinant Mouse Ifnlr1 (Accession # AAH57856) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Mouse
• Tag: Fc Chimera
• Predicted N Terminal: Arg21
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.1 µg/mL of rmIL-28 R alpha Fc Chimera was mixed with serially diluted rmIL-28B. Following incubation, the IL-28 R alpha rmIL-28B complex was captured in a goat anti-mFc-coated plate. Bound IL-28B was measured using biotinylated goat anti-mIL-28B. The concentration of rmIL-28B that produces 50% of the optimal binding was found to be approximately 0.7 - 3.5 µg/mL.
• Molecular Mass: Recombinant Mouse Ifnlr1, Fc Chimera has a calculated MW of 50.6 kDa (monomer). In SDS-PAGE migrates as 62-70 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Ifnlr1 interferon lambda receptor 1 [ Mus musculus (house mouse) ]
• Official Symbol: Ifnlr1
• Synonyms: Ifnlr1; interferon lambda receptor 1; Il28ra; CRF2-12; interferon lambda receptor 1; IFN-lambda R1; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; class II cytokine receptor 12; cytokine receptor class-II member 12; cytokine receptor family 2 member 12; interferon-lambda receptor 1; interleukin 28 receptor alpha; interleukin-28 receptor subunit alpha
• Gene ID: 242700
• mRNA Refseq: NM_174851
• Protein Refseq: NP_777276
• UniProt ID: Q8CGK5
• Chromosome Location: 4; 4 D3