Recombinant Human RGMB protein, His-tagged

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Recombinant Human RGMB protein, His-tagged

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Cat.No. : RGMB-345H
Product Overview : Recombinant Human RGMB(Gly87-Asp209 (N-terminus chain) & Pro210-Ser452 (C-terminus chain)) fused with His tag at C-terminal was expressed in NS0.
Source : NS0
Species : Human
Tag : His
Predicted N Terminal : Gly87 & Pro210
Form : Lyophilized from a 0.2 μm filtered solution in PBS.
Bio-activity : Measured by its binding ability in a functional ELISA. Immoblized rhBMP-4 at 1 µg/mL (100 µL/well) can bind rhRGM-B with a linear range of 10-500 ng/mL.
Molecular Mass : Predicted Molecular Mass: 13.4 (N-terminus chain), 27.7 (C-terminus chain) kDa;SDS-PAGE: 20 kDa and 35 kDa, reducing conditions.
Protein length : Gly87-Asp209 (N-terminus chain) & Pro210-Ser452 (C-terminus chain)
Endotoxin : <0.01 EU per 1 μg of the protein by the LAL method.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Storage : Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 100 μg/mL in sterile PBS.
Gene Name : RGMB RGM domain family, member B [ Homo sapiens ]
Official Symbol : RGMB
Synonyms : RGMB; RGM domain family, member B; RGM domain family member B; FLJ90406; repulsive guidance molecule B; DRG11-responsive axonal guidance and outgrowth of neurite; DRAGON; MGC86970; DKFZp434P228;
Gene ID : 285704
mRNA Refseq : NM_001012761
Protein Refseq : NP_001012779
MIM : 612687
UniProt ID : Q6NW40
Chromosome Location : 5q21.1
Pathway : Axon guidance, organism-specific biosystem; BMP receptor signaling, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Netrin-1 signaling, organism-specific biosystem;
Function : identical protein binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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