"LY96" Related Products


Recombinant Human LY96 protein, His-tagged

Cat.No.: LY96-445H
Product Overview: Recombinant Human LY96(Glu17 - Asn160) fused with His tag at C-terminal was expressed in E. coli.
Source: E. coli
Species: Human
Tag: His
Predicted N Terminal: Met
Form: Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Bio-activity: Measured by its binding ability in a functional ELISA. When recombinant human TLR-4 is Immobilized at 2 µg/mL (100 µL/well), the concentration of rhMD-2 that produces 50% optimal binding response is found to be approximately 0.03-0.15 µg/mL.
Molecular Mass: Predicted Molecular Mass: 19.2 (monomer) kDa
Protein length: Glu17 - Asn160
Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution: Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Gene Name: LY96 lymphocyte antigen 96 [ Homo sapiens ]
Official Symbol: LY96
Synonyms: LY96; lymphocyte antigen 96; MD 2; protein MD-2; myeloid differentiation protein-2; MD2; MD-2; ly-96; ESOP-1;
Gene ID: 23643
mRNA Refseq: NM_001195797
Protein Refseq: NP_001182726
MIM: 605243
UniProt ID: Q9Y6Y9
Chromosome Location: 8q13.3
Pathway: Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; IKK complex recruitment mediated by RIP1, organism-specific biosystem; IRAK2 mediated activation of TAK1 complex, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88 cascade initiated on plasma membrane, organism-specific biosystem;
Function: coreceptor activity; lipopolysaccharide receptor activity; protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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