Recombinant Human IGFBP2, Met-tagged IGFBP2-477H

Recombinant Human IGFBP2, Met-tagged

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Recombinant Human IGFBP2, Met-tagged

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Cat.No. : IGFBP2-477H
Product Overview : Recombinant Human IGFBP2 (Accession # CAA34373) Glu40-Gln328, fused with an N-terminal Met, was produced in Mouse myeloma cell line, NS0-derived.
Source : NSO cells
Species : Human
Predicted N Terminal : Met
Form : Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.
Bio-activity : Measured by its ability to inhibit the biological activity of IGF-I or IGF-II on MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083.The ED50 for this effect is typically 0.03 - 0.09 µg/mL in the presence of 14 ng/mL rhIGF-II.
Molecular Mass : Recombinant Human IGFBP2, Met-tagged has a calculated MW of 31 kDa. In SDS-PAGE migrates as 36 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : IGFBP2 insulin-like growth factor binding protein 2, 36kDa [ Homo sapiens ]
Official Symbol : IGFBP2
Synonyms : IGFBP2; insulin-like growth factor binding protein 2, 36kDa; IBP2, insulin like growth factor binding protein 2 (36kD); insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2; IBP2; IGF-BP53;
Gene ID : 3485
mRNA Refseq : NM_000597
Protein Refseq : NP_000588
MIM : 146731
UniProt ID : P18065
Chromosome Location : 2q33-q34

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