Recombinant Human IGFBP2, Met-tagged


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Recombinant Human IGFBP2, Met-tagged

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Cat.No. : IGFBP2-477H
Product Overview : Recombinant Human IGFBP2 (Accession # CAA34373) Glu40-Gln328, fused with an N-terminal Met, was produced in Mouse myeloma cell line, NS0-derived.
Source : NSO cells
Species : Human
Predicted N Terminal : Met
Form : Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.
Bio-activity : Measured by its ability to inhibit the biological activity of IGF-I or IGF-II on MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083.The ED50 for this effect is typically 0.03 - 0.09 µg/mL in the presence of 14 ng/mL rhIGF-II.
Molecular Mass : Recombinant Human IGFBP2, Met-tagged has a calculated MW of 31 kDa. In SDS-PAGE migrates as 36 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : IGFBP2 insulin-like growth factor binding protein 2, 36kDa [ Homo sapiens ]
Official Symbol : IGFBP2
Synonyms : IGFBP2; insulin-like growth factor binding protein 2, 36kDa; IBP2, insulin like growth factor binding protein 2 (36kD); insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2; IBP2; IGF-BP53;
Gene ID : 3485
mRNA Refseq : NM_000597
Protein Refseq : NP_000588
MIM : 146731
UniProt ID : P18065
Chromosome Location : 2q33-q34
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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