Recombinant Human CR1 protein, His-tagged CR1-506H

Recombinant Human CR1 protein, His-tagged

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Recombinant Human CR1 protein, His-tagged

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Cat.No. : CR1-506H
Product Overview : Recombinant Human CR1(Gln42-Asp1971) fused with a C-terminal 10-His tag and a substitution of His1208Arg was expressed in NS0.
Source : NS0
Species : Human
Tag : His
Predicted N Terminal : Gln42 predicted
Form : Lyophilized from a 0.2 μm filtered solution in PBS.
Bio-activity : Measured by its binding ability in a functional ELISA. When rhCD35 is coated at 5 μg/mL, complement component C3b binds with an apparent KD <10 nM.
Molecular Mass : Predicted Molecular Mass: 213 kDa;SDS-PAGE: 200-220 kDa, reducing conditions.
Endotoxin : <0.10 EU per 1 μg of the protein by the LAL method
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Storage : Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 400 μg/mL in PBS.
Gene Name : CR1 complement component (3b/4b) receptor 1 (Knops blood group) [ Homo sapiens ]
Official Symbol : CR1
Synonyms : CR1; complement component (3b/4b) receptor 1 (Knops blood group); complement component (3b/4b) receptor 1, including Knops blood group system; complement receptor type 1; CD35; KN; CD35 antigen; C3b/C4b receptor; C3-binding protein; Knops blood group antigen; complement component receptor 1; C3BR; C4BR;
Gene ID : 1378
mRNA Refseq : NM_000573
Protein Refseq : NP_000564
MIM : 120620
UniProt ID : P17927
Chromosome Location : 1q32
Pathway : Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Immune System, organism-specific biosystem;
Function : complement component C3b binding; complement component C3b receptor activity; complement component C4b binding; complement component C4b receptor activity; receptor activity;

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