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Active Recombinant Human CR1 protein, His-tagged

Cat.No. : CR1-506H
Product Overview : Recombinant Human CR1(Gln42-Asp1971) fused with a C-terminal 10-His tag and a substitution of His1208Arg was expressed in NS0.
  • Specification
  • Gene Information
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Source : Mammalian cells
Species : Human
Tag : His
Predicted N Terminal : Gln42 predicted
Form : Lyophilized from a 0.2 μm filtered solution in PBS.
Bio-activity : Measured by its binding ability in a functional ELISA. When rhCD35 is coated at 5 μg/mL, complement component C3b binds with an apparent KD <10 nM.
Molecular Mass : Predicted Molecular Mass: 213 kDa;SDS-PAGE: 200-220 kDa, reducing conditions.
Endotoxin : <0.10 EU per 1 μg of the protein by the LAL method
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
Storage : Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 400 μg/mL in PBS.
Gene Name : CR1 complement component (3b/4b) receptor 1 (Knops blood group) [ Homo sapiens ]
Official Symbol : CR1
Synonyms : CR1; complement component (3b/4b) receptor 1 (Knops blood group); complement component (3b/4b) receptor 1, including Knops blood group system; complement receptor type 1; CD35; KN; CD35 antigen; C3b/C4b receptor; C3-binding protein; Knops blood group antigen; complement component receptor 1; C3BR; C4BR;
Gene ID : 1378
mRNA Refseq : NM_000573
Protein Refseq : NP_000564
MIM : 120620
UniProt ID : P17927
Chromosome Location : 1q32
Pathway : Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Immune System, organism-specific biosystem;
Function : complement component C3b binding; complement component C3b receptor activity; complement component C4b binding; complement component C4b receptor activity; receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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