Active Recombinant Human TREML2, Fc Chimera

• Cat.No.: TREML2-521H
• Product Overview: Recombinant Human TREML2 (Accession # CAI19909) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc Chimera
• Predicted N Terminal: Gly78
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells.Human PBMC cultured for 72 hours with PHA were incubated for an additional 3 days in 96 well plates coated with anti-CD3 and recombinant human TREML2/Fc Chimera.The ED50 for this effect is typically 0.45 - 1.8 µg/mL.Optimal dilutions should be determined by each laboratory for each applications.
• Molecular Mass: Recombinant Human TREML2, Fc Chimera has a calculated MW of 53.7 kDa (monomer). In SDS-PAGE migrates as 75-100 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: TREML2 triggering receptor expressed on myeloid cells-like 2 [ Homo sapiens ]
• Official Symbol: TREML2
• Synonyms: TREML2; triggering receptor expressed on myeloid cells-like 2; C6orf76, chromosome 6 open reading frame 76; trem-like transcript 2 protein; dJ238O23.1; FLJ13693; TLT2; TREM like transcript 2; triggering receptor expressed on myeloid cells-like protein 2; TLT-2; C6orf76; MGC149715; MGC149716
• Gene ID: 79865
• mRNA Refseq: NM_024807
• Protein Refseq: NP_079083
• MIM: 609715
• UniProt ID: Q5T2D2
• Chromosome Location: 6p21.1