Active Recombinant Human LIFR

• Cat.No.: LIFR-687H
• Product Overview: Recombinant Human LIFR (Accession # NP_001121143) Met1-Ser833 was produced in Human embryonic kidney cell, HEK293-derived.

Specification

• Source: HEK293 cells
• Species: Human
• Predicted N Terminal: Gln45 predicted: No result obtained, sequencing might be blocked
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit LIF-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323.The ED50 for this effect is typically 1-6 µg/mL in the presence of 0.3 ng/mL of recombinant human LIF.
• Molecular Mass: Recombinant Human LIFR has a calculated MW of 89.4 kDa. In SDS-PAGE migrates as 110-140 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: LIFR leukemia inhibitory factor receptor alpha [ Homo sapiens ]
• Official Symbol: LIFR
• Synonyms: LIFR; leukemia inhibitory factor receptor alpha; leukemia inhibitory factor receptor; CD118; LIF receptor; CD118 antigen; SWS; SJS2; STWS; LIF-R; FLJ98106; FLJ99923
• Gene ID: 3977
• mRNA Refseq: NM_001127671
• Protein Refseq: NP_001121143
• MIM: 151443
• UniProt ID: P42702
• Chromosome Location: 5p13-p12