| Cat.No.: | ITGAM&ITGB2-692H |
| Product Overview: | Recombinant Human ITGAM&ITGB2 (Accession # NP_001139280 (Integrin alpha M) & P05107 (Integrin beta 2)) was produced in Chinese Hamster Ovary cell line, CHO-derived. |
| Source: | CHO cells |
| Species: | Human |
| Predicted N Terminal: | Phe17 (Integrin alpha M) & No results obtained: Gln23 predicted (Integrin beta 2) |
| Form: | Lyophilized from a 0.2 µm filtered solution in Tris, NaCl and MgCl2. |
| Bio-activity: | Measured by the ability of the immobilized protein to support the adhesion of CHO Chinese hamster ovary cells transfected with ICAM-1.The ED50 for this effect is typically 0.25-1.5 µg/mL. |
| Molecular Mass: | Recombinant Human ITGAM&ITGB2 has a calculated MW of 124.7 kDa (Integrin alpha M), 79 kDa (Integrin beta 2). In SDS-PAGE migrates as 165 kDa and 100 kDa, reducing conditions. |
| Purity: | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
| Storage: | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
| Gene Name: | ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) [ Homo sapiens ] |
| Official Symbol: | ITGAM |
| Synonyms: | ITGAM; integrin, alpha M (complement component 3 receptor 3 subunit); CD11B, CR3A, integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide); integrin alpha-M; CD11b; MAC 1; CR-3 alpha chain; antigen CD11b (p170); leukocyte adhesion receptor MO1; CD11 antigen-like family member B; macrophage antigen alpha polypeptide; cell surface glycoprotein MAC-1 subunit alpha; neutrophil adherence receptor alpha-M subunit; CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; MGC117044; |
| Gene ID: | 3684 |
| mRNA Refseq: | NM_000632 |
| Protein Refseq: | NP_000623 |
| MIM: | 120980 |
| UniProt ID: | P11215 |
| Chromosome Location: | 16p11.2 |
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