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Active Recombinant Human ITGAM&ITGB2

Cat.No. : ITGAM&ITGB2-692H
Product Overview : Recombinant Human ITGAM&ITGB2 (Accession # NP_001139280 (Integrin alpha M) & P05107 (Integrin beta 2)) was produced in Chinese Hamster Ovary cell line, CHO-derived.
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Source : CHO cells
Species : Human
Predicted N Terminal : Phe17 (Integrin alpha M) & No results obtained: Gln23 predicted (Integrin beta 2)
Form : Lyophilized from a 0.2 µm filtered solution in Tris, NaCl and MgCl2.
Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of CHO Chinese hamster ovary cells transfected with ICAM-1.The ED50 for this effect is typically 0.25-1.5 µg/mL.
Molecular Mass : Recombinant Human ITGAM&ITGB2 has a calculated MW of 124.7 kDa (Integrin alpha M), 79 kDa (Integrin beta 2). In SDS-PAGE migrates as 165 kDa and 100 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) [ Homo sapiens ]
Official Symbol : ITGAM
Synonyms : ITGAM; integrin, alpha M (complement component 3 receptor 3 subunit); CD11B, CR3A, integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide); integrin alpha-M; CD11b; MAC 1; CR-3 alpha chain; antigen CD11b (p170); leukocyte adhesion receptor MO1; CD11 antigen-like family member B; macrophage antigen alpha polypeptide; cell surface glycoprotein MAC-1 subunit alpha; neutrophil adherence receptor alpha-M subunit; CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; MGC117044;
Gene ID : 3684
mRNA Refseq : NM_000632
Protein Refseq : NP_000623
MIM : 120980
UniProt ID : P11215
Chromosome Location : 16p11.2

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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