Recombinant Human ITGAM&ITGB2 ITGAM&ITGB2-692H

Recombinant Human ITGAM&ITGB2

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Recombinant Human ITGAM&ITGB2

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Cat.No. : ITGAM&ITGB2-692H
Product Overview : Recombinant Human ITGAM&ITGB2 (Accession # NP_001139280 (Integrin alpha M) & P05107 (Integrin beta 2)) was produced in Chinese Hamster Ovary cell line, CHO-derived.
Source : CHO cells
Species : Human
Predicted N Terminal : Phe17 (Integrin alpha M) & No results obtained: Gln23 predicted (Integrin beta 2)
Form : Lyophilized from a 0.2 µm filtered solution in Tris, NaCl and MgCl2.
Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of CHO Chinese hamster ovary cells transfected with ICAM-1.The ED50 for this effect is typically 0.25-1.5 µg/mL.
Molecular Mass : Recombinant Human ITGAM&ITGB2 has a calculated MW of 124.7 kDa (Integrin alpha M), 79 kDa (Integrin beta 2). In SDS-PAGE migrates as 165 kDa and 100 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) [ Homo sapiens ]
Official Symbol : ITGAM
Synonyms : ITGAM; integrin, alpha M (complement component 3 receptor 3 subunit); CD11B, CR3A, integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide); integrin alpha-M; CD11b; MAC 1; CR-3 alpha chain; antigen CD11b (p170); leukocyte adhesion receptor MO1; CD11 antigen-like family member B; macrophage antigen alpha polypeptide; cell surface glycoprotein MAC-1 subunit alpha; neutrophil adherence receptor alpha-M subunit; CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; MGC117044;
Gene ID : 3684
mRNA Refseq : NM_000632
Protein Refseq : NP_000623
MIM : 120980
UniProt ID : P11215
Chromosome Location : 16p11.2

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