Recombinant Human GDF1 GDF1-715H

Recombinant Human GDF1

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Recombinant Human GDF1

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Cat.No. : GDF1-715H
Product Overview : Recombinant Human GDF1 (Accession # NP_001483) Asp254-Arg372 was produced in Chinese Hamster Ovary cell line, CHO-derived.
Source : CHO cells
Species : Human
Predicted N Terminal : Asp254
Form : Lyophilized from a 0.2 µm filtered solution in HCl with BSA as a carrier protein.
Bio-activity : Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells. Mazerbourg, S. et al. (2004) Mol. Endocrinol. 18:653.50 ng/mL of Recombinant Human GDF-1 can effectively induce Smad2 phosphorylation.
Molecular Mass : Recombinant Human GDF1 has a calculated MW of 12.6 kDa (monomer). In SDS-PAGE migrates as 13 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 100 µg/mL in 4 mM HCl containing at least 0.1% human or bovine serum albumin.
Gene Name : ITGAV integrin, alpha V [ Homo sapiens ]
Official Symbol : ITGAV
Synonyms : ITGAV; integrin, alpha V; antigen identified by monoclonal L230 , integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , MSK8, vitronectin receptor , VNRA, VTNR; integrin alpha-V; CD51; integrin alphaVbeta3; vitronectin receptor subunit alpha; antigen identified by monoclonal L230; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); MSK8; VNRA; VTNR; DKFZp686A08142;
Gene ID : 3685
mRNA Refseq : NM_001144999
Protein Refseq : NP_001138471
MIM : 193210
UniProt ID : P06756
Chromosome Location : 2q31-q32

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