Active Recombinant Human ITGA2&ITGB1

• Cat.No.: ITGA2&ITGB1-738H
• Product Overview: Recombinant Human ITGA2&ITGB1 (Accession # NP_002194 (Integrin alpha 2) & P05556 (Integrin beta 1)) was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Source: CHO cells
• Species: Human
• Predicted N Terminal: Tyr30 ( alpha 2) & No results obtained, Gln21 predicted ( beta 1)
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.When bovine collagen-II is coated at 10 µg/mL, Recombinant Human Integrin alpha 2 beta 1 binds with an apparent KD <1nM.
• Molecular Mass: Recombinant Human ITGA2&ITGB1 has a calculated MW of 126 kDa ( alpha 2) & 83.3 kDa ( beta 1). In SDS-PAGE migrates as 140-150 kDa ( alpha 2) & 120-130 kDa ( beta 1), reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) [ Homo sapiens ]
• Official Symbol: ITGA2
• Synonyms: ITGA2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); CD49B; integrin alpha-2; CD49b; integrin alpha 2; collagen receptor; VLA-2 subunit alpha; platelet antigen Br; platelet glycoprotein Ia; platelet glycoprotein GPIa; CD49 antigen-like family member B; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; BR; GPIa; VLA-2; VLAA2; BDPLT9
• Gene ID: 3673
• mRNA Refseq: NM_002203
• Protein Refseq: NP_002194
• MIM: 192974
• UniProt ID: P17301
• Chromosome Location: 5q11.2