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Recombinant Human ITGAV/ITGB3 protein, His-tagged

Cat.No. : ITGAV&ITGB3-739H
Product Overview : Recombinant Human ITGAV(Phe 31 - Val 992)/ITGB3(Gly 27 - Asp 718), subunit ITGAV is fused with polyhistidine tag at the C-terminus and followed by a acidic tail and subunit ITGB3 contains no tag but a basic tail at the C-terminus was expressed in HEK293.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : His
Predicted N Terminal : The predicted N-terminus is Phe 31 (ITGAV) & Gly 27 (ITGB3).
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Molecular Mass : Has a calculated MW of 113 kDa (ITGAV) and 81.8 kDa (ITGB3). The predicted N-terminus is Phe 31 (ITGAV) & Gly 27 (ITGB3). The reducing (R) protein migrates as 145 kDa (ITGAV) and 100-116 kDa (ITGB3) respectively due to glycosylation.
Protein length : Phe 31 - Val 992 (ITGAV) & Gly 27 - Asp 718 (ITGB3)
Endotoxin : Less than 1.0 EU per μg of the Human ITGAV & ITGB3 Heterodimer Protein by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade).
Gene Name : ITGAV integrin, alpha V [ Homo sapiens ]
Official Symbol : ITGAV
Synonyms : ITGAV; integrin, alpha V; antigen identified by monoclonal L230 , integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , MSK8, vitronectin receptor , VNRA, VTNR; integrin alpha-V; CD51; integrin alphaVbeta3; vitronectin receptor subunit alpha; antigen identified by monoclonal L230; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); MSK8; VNRA; VTNR; DKFZp686A08142;
Gene ID : 3685
mRNA Refseq : NM_001144999
Protein Refseq : NP_001138471
MIM : 193210
UniProt ID : P06756
Chromosome Location : 2q31-q32
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Axon guidance, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem;
Function : contributes_to insulin-like growth factor I binding; contributes_to opsonin binding; protein binding; protein kinase C alpha binding; contributes_to protein kinase C binding; receptor activity; transforming growth factor beta binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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