"ITGAV&ITGB6" Related Products

Recombinant Human ITGAV&ITGB6

Cat.No.: ITGAV&ITGB6-741H
Product Overview: Recombinant Human ITGAV&ITGB6 (Accession # NP_002201 (Integrin alpha V) & P18564 (Integrin beta 6)) was produced in Chinese Hamster Ovary cell line, CHO-derived.
Source: CHO cells
Species: Human
Predicted N Terminal: Phe31 ( alpha V subunit) & Gly22 ( beta 6 subunit)
Form: Lyophilized from a 0.2 µm filtered solution in Tris, NaCl and CaCl2.
Bio-activity: Measured by its binding ability in a functional ELISA.Immobilized Recombinant Human Integrin alpha V beta 6 at 2.0 µg/mL can bind Recombinant Human LAP TGF-beta 1 with an apparent KD <0.1 nM.
Molecular Mass: Recombinant Human ITGAV&ITGB6 has a calculated MW of 110.5 kDa ( alpha V subunit), 78.6 kDa ( beta 6 subunit). In SDS-PAGE migrates as 145 kDa and 115 kDa, reducing conditions.
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name: ITGAV integrin, alpha V [ Homo sapiens ]
Official Symbol: ITGAV
Synonyms: ITGAV; integrin, alpha V; antigen identified by monoclonal L230 , integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , MSK8, vitronectin receptor , VNRA, VTNR; integrin alpha-V; CD51; integrin alphaVbeta3; vitronectin receptor subunit alpha; antigen identified by monoclonal L230; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); MSK8; VNRA; VTNR; DKFZp686A08142;
Gene ID: 3685
mRNA Refseq: NM_001144999
Protein Refseq: NP_001138471
MIM: 193210
UniProt ID: P06756
Chromosome Location: 2q31-q32

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