Recombinant Human MBNL1, MYC/DDK-tagged
Cat.No. : | MBNL1-2742H |
Product Overview : | Recombinant full-length Human MBNL1, transcript variant 3, fused with C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | Muscleblind-like (Drosophila), also known as MBNL1, is a protein that in humans is encoded by the MBNL1 gene. It has been implicated in Myotonic dystrophy and has been shown to autoregulate its transcript. Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. |
Source : | HEK293 cells |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 41.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | MBNL1 muscleblind-like splicing regulator 1 [ Homo sapiens ] |
Official Symbol : | MBNL1 |
Synonyms : | EXP; MBNL; EXP35; EXP40; EXP42; muscleblind-like protein 1; triplet-expansion RNA-binding protein |
Gene ID : | 4154 |
mRNA Refseq : | NM_207293 |
Protein Refseq : | NP_997176 |
MIM : | 606516 |
UniProt ID : | Q9NR56 |
Chromosome Location : | 3q25 |
Pathway : | Adipogenesis, organism-specific biosystem |
Function : | RNA binding; double-stranded RNA binding; metal ion binding |
Products Types
◆ Recombinant Protein | ||
MBNL1-241H | Recombinant Human MBNL1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
Mbnl1-3982M | Recombinant Mouse Mbnl1 Protein, Myc/DDK-tagged | +Inquiry |
MBNL1-2738H | Recombinant Human MBNL1, MYC/DDK-tagged | +Inquiry |
MBNL1-30258TH | Recombinant Human MBNL1 | +Inquiry |
MBNL1-3978C | Recombinant Chicken MBNL1 | +Inquiry |
◆ Lysates | ||
MBNL1-4441HCL | Recombinant Human MBNL1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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