Active Recombinant Mouse Lrp5 Protein, His-tagged

• Cat.No.: Lrp5-608M
• Product Overview: Recombinant Mouse Lrp5 (Accession # NP_032539) Met1-Ser1383, fused with a C-terminal 6-His tag, was produced in Human embryonic kidney cell, HEK293-derived.

Specification

• Source: HEK293 Cells
• Species: Mouse
• Tag: His
• Predicted N Terminal: Ser31
• Form: Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
• Bio-activity: Measured by its binding ability in a functional ELISA.When biotinylated rhDKK-1 is immobilized at 0.25 µg/mL on a streptavidin-coated plate, recombinant mouse LRP-5 binds with an apparent KD < 15 nM.
• Molecular Mass: Recombinant Mouse Lrp5, His-tagged has a calculated MW of 152.1 kDa. In SDS-PAGE migrates as 160 kDa, reducing conditions.
• Protein length: Met1-Ser1383
• Purity: >85%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Publication:
  Development of selective bispecific Wnt mimetics for bone loss and repair (2021)

Gene Information

• Gene Name: Lrp5 low density lipoprotein receptor-related protein 5 [ Mus musculus ]
• Official Symbol: Lrp5
• Synonyms: LRP5; low density lipoprotein receptor-related protein 5; low-density lipoprotein receptor-related protein 5; LRP-5; LRP-7; low-density lipoprotein receptor-related protein 7; HBM; LR3; LRP7; OPPG; BMND1; mKIAA4142; KIAA4142
• Gene ID: 16973
• mRNA Refseq: NM_008513
• Protein Refseq: NP_032539