Active Recombinant Mouse Mstn Protein, Fc Chimera
Cat.No. : | Mstn-649M |
Product Overview : | Recombinant Mouse Mstn (Accession # NP_034964), fused with , was produced in Mouse myeloma cell line, NS0-derived. |
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Source : | Mammalian cells |
Species : | Mouse |
Tag : | Fc |
Predicted N Terminal : | Asn25 |
Form : | Lyophilized from a 0.2 µm filtered solution in MES, NaCl and CHAPS with BSA as a carrier protein. |
Bio-activity : | Measured by its ability to inhibit rmGDF-8 activity in K562 human chronic myelogenous leukemia cells. Thies, R.S. et al. (2001) Growth Factors 18:251.The ED50 for this effect is typically 0.03-0.15 µg/mL in the presence of 40 ng/mL of Recombinant Mouse GDF-8/Myostatin. |
Molecular Mass : | Recombinant Mouse Mstn, Fc Chimera has a calculated MW of 54.9 kDa (monomer). In SDS-PAGE migrates as 66 kDa, reducing conditions. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | Mstn myostatin [ Mus musculus ] |
Official Symbol : | Mstn |
Synonyms : | MSTN; myostatin; growth/differentiation factor 8; GDF-8; compact; growth differentiation factor 8; Cmpt; Gdf8; MGC124261; MGC124262; MGC124263; |
Gene ID : | 17700 |
mRNA Refseq : | NM_010834 |
Protein Refseq : | NP_034964 |
MIM : |
Products Types
◆ Recombinant Protein | ||
Mstn-91M | Recombinant Mouse Mstn Protein, His (Fc)-Avi-tagged | +Inquiry |
MSTN-2458H | Recombinant Human MSTN Protein, His-tagged | +Inquiry |
MSTN-2089H | Recombinant Human MSTN Protein, MYC/DDK-tagged | +Inquiry |
MSTN-2700R | Recombinant Rhesus Macaque MSTN Protein, His (Fc)-Avi-tagged | +Inquiry |
MSTN-210H | Recombinant Human Myostatin Propeptide | +Inquiry |
◆ Lysates | ||
MSTN-2229MCL | Recombinant Mouse MSTN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMSTN inhibitors work by blocking the activity of the MSTN protein, thus promoting muscle growth and potentially reversing muscle loss.
Some potential side effects include joint stiffness, increased risk of fractures, and insulin resistance, which require close monitoring during trials.
Overexpression of MSTN can lead to muscle atrophy and decreased muscle mass.
Researchers carefully monitor the dosage and administration of MSTN protein therapy through preclinical and clinical studies to establish the optimal therapeutic dose.
Possible risks include unintended effects on other organ systems and potential complications related to excessive muscle growth.
Customer Reviews (3)
Write a reviewThe MSTN protein surpasses expectations in terms of quality and will undoubtedly fulfill my experimental requirements.
the manufacturer of MSTN provides exceptional technical support, offering valuable assistance in troubleshooting and experimental design.
The outstanding level of customer service adds extra reassurance and confidence in using the MSTN protein for my scientific investigations.
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